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potassium and sodium
Terms in this set (27)
principal cells promote ______ reabsorption and ____ secretion
in principal cells, what channel promotes K+ secretion
in principal cells, what channel promotes Na+ reabsorption
alpha-intercalated cells control rate of ____ reabsorption
alpha-intercalated cells' mechanism occurs in high or low K+ intake/diet?
low K+ intake
where 67% of filtered K+ is reabsorbed
Where is the NKCC2 transporter located to reabsorb Na+?
thick ascending limb
where are principal cells located?
late distal tubule and collecting ducts
What blocks luminal Na+ (EnaC) channels?
_____ antagonizes action of aldosterone in principal cells
_____ blocks chloride binding leading to prevention of sodium reabsorption
in the thick ascending limb, Na+ reabsorption occurs causing a(n) ___________________ to help drive reabsorption of cations such as Ca++ and Mg++
where do we see Na+ act as a cotransporter and as an antiport utilizing NHE3
early proximal tubule
the late proximal tubule primarily reabsorbs ______
Where is there a NaCl cotransporter?
early distal tubule
most important hormone that shifts K+ into cells after a meal
insulin, epinephrine (as a β-adrenergic agonist), and aldosterone all promote the transfer of K+ from extracellular to intracellular fluid through the ubiquitous ___________
which catecholamine causes a shift of K+ into cells?
which catecholamine causes a shift of K+ out of cells/blocks uptake?
lack of insulin (untreated diabetes mellitus) or a deficient renin-angiotensin-aldosterone system can significantly compromise tolerance to K+ loading and can predispose to __________
too much aldosterone can cause hypo or hyperkalemia?
if you are experiencing severe burns on your body are you more likely to suffer from hypo or hyperkalemia?
acidemia leads to hyper or hypokalemia?
alkalemia leads to hyper or hypokalemia?
in a low K+ diet, the principal cells increase K+ reabsorption by _____________ cells
aldosterone promotes ____ reabsorption and _____ secretion/excretion
loop diuretics increase K+ excretion by blocking _______
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