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Connective Tissue Diseases
Terms in this set (91)
What causes Lupus pernio?
What causes Lupus vulgaris?
What is the distribution of the rash caused by lupus erythematosus?
-sun exposed areas of upper trunk and arms
Is Discoid LE a benign variant of SLE?
There are two types of Discoid LE, localized and disseminated. What are the differences?
-localized is confined to the face above the chin, scalp and the ears
-disseminated- lesions occur elsewhere
Describe the rash caused by Discoid LE.
What disease is associated with a "thumb tacking" follicular scale?
What shape are discoid LE rashes usually?
they are often annular
What percent of discoid LE patients develope SLE?
What does discoid LE look like?
What layer of the skin is primarily affected in discoid LE?
basal layer with a marked inflammatory infiltrate
How does Discoid LE heal?
new lesions are red, then they get hyperpigmented and then can turn hypopigmented
Does rash from Discoid LE heal without a scar?
What does "thumb tacking" look like?
What does the "annular" rash formed by Discoid LE look like?
discoid lupus erythematosus on the sclap
Discoid lupus in a rosaceous pattern
-seen in 7.5% of patients
What is the percent of patients with disseminated discoid LE that will go on to develop SLE?
up to 20%
What does disseminated discoid LE look like?
similar to discoid, just widened distribution
*found on sun exposed surfaces
disseminated discoid LE
Can disseminated discoid LE appear on the palms of the hands?
disseminated discoid LE.
disseminated discoid LE..
healed disseminated discoid LE
Warty lesions of the feet in chronic lupus erythematosis
What are the characteristics of subacute cutaneous lupus erythematosus (SCLE)?
What percentage of patients with subacute cutaneous lupus erythematosus will go on to get SLE?
What disease is associated with antibodies to Ro/SS-A expressed on keratinocytes, seen when exposed to UV light?
subacute cutaneous lupus erythematosus
What does subacute cutaneous lupus erythematosus look like?
subacute cutaneous lupus erythematosus showing annular polycyclic lesions
SCLE with annular lesions
What type of lupus is also known as ANA negative lupus?
subacute cutaneous lupus erythematosis
What are the symptoms needed to diagnose SLE?
you only need 4 of these
What are the characteristics of systemic lupus erythematosus?
With lupus, what part of the skin thickens?
What are LE cells?
What are the skin manifestations of SLE?
What does a malar rash look like?
What does telangiectatic lupus erythematosus look like?
SLE lesions on the hard palate
almost always means SLE
What is Chilblain leasions associated with?
keratoderma produced by SLE
bullous lupus erythematosis
What are the characteristics of neonatal lupus?
What does neonatal lupus look like?
What are the characteristics of Dermatomyositis?
What are the characteristics of the rash caused by dermatomyositis?
What disease is common to produce a rash that is violaceous and edematous of the upper eyelids (heliotropic)?
What is Gottron's sign and what is it characteristic of?
rash on the dorsal surface of the knuckles
What does the rash of dermatomyositis look like?
The rash caused by dermatomyositis can also appear on sun exposed areas.
Signs of dermatomyositis around the nail fold.
What does dermatomyositis look like under the microscope?
What are the characteristics for scleroderma?
What is CREST syndrome?
What does cutaneous clacinosis look like in scleroderma?
Is scleroderma a systemic or localized disease?
What are the characteristics of morphea?
What does morphea look and feel like?
-ivory white or waxy colored plaques
-hard woody immobile feel on palpation
What are the different forms of Morphea?
*Morphea is a localized form of scleroderma, but morphea has a generalized form
What is the key finding microscopically of morphea?
a lot of collagen
What does morphea look like?
hard waxy appearing plaque
What does the linear form of morphea look like? What is another name for it if it occurs on the face?
en coup de sabre
en coupe de sabre
linear morphea on the head
What does linear morphea look like on the foot?
What does localized morphea look like?
What are the characteristics of progressive systemic sclerosis (PSS)?
What are some facial signs of systemic sclerosis?
hard to open mouth too
"cobblestone" appearance due to clacinosis in systemic sclerosis (scleroderma).
telangiectasias in scleroderma
What are the characteristics of relapsing polychondritis?
-intermittent episodes of inflammation of articular and nonarticular cartilage eventuates in chondrolysis and collapse of involved cartilage
What does relapsing polychondritis look like in the ear?
What are the characteristics of Rheumatoid nodules?
What do rheumatoid nodules look like on the hand?
rheumatoid nodules on the elbow
rheumatoid nodules on the knee
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