Chronic Lymphocytic Leukemia (CLL)
1. cancer of the lymphocytic stem cells proliferation of neoplastic B cells and T cells (well differentiated)
2. lymphocytosis, lymphadenopathy, splenomegaly, autoimmune hemolytic anemia and immune-mediated thrombocytopenia.
3. symptoms: fatigue, ↓exercise capacity, enlargement of superficial lymph nodes, splenomegaly, recurrent infections, pallor, edema, and vein inflammation
4. treatment: chemotherapy, monoclonal antibodies, corticosteroids, or splenectomy