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Immotile Cilia Syndrome (symptoms)
immotile spermatozoa, male infertility, & chronic respiratory infections
lysosomal storage disease; glycolipids are endocytosed & accumulate in neurons of brain
(chemo drug) microtubule assembly disruptor used to prevent cell division & tumor growth
Marfan's Syndrome (consequence)
abnormal elastic tissue (e.x. hyperextendible joints, hernias, & enormous dilation of aorta)
Basal Cell Carcinoma
skin cancer arises from stratum basale (containing sebaceous glands) & invades dermis
Basal Cell Carcinoma (characteristic)
small shiny bump (enlarges into a central depression, beaded "pearly" edge)
Squamous Cell Carcinoma
skin cancer arises from keratinocytes in stratum spinosum; penetrates the dermis
Squamous Cell Carcinoma (characteristic)
raised, reddened, scaly appearance (later forming concave ulcer with raised edges)
Malignant Melanoma (characteristic)
ABCD - asymmetry, border irregular, color mixed, & diameter over 6 mm
failure of cartilage growth; long bones stop growing; normal torso, short limbs
Long term risk of PPI's
increase in fracture due to no calcium absorption in stomach (no acidification)
Rotator Cuff Tears
tears of 1 or more of the 4 tendons of the rotator cuff muscles (most typically involves the supraspinatus muscle)
autoimmune attack on the joints (synovial membrane); symmetrical inflammation of joints
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