millionnaire

what drug is a prodrug of 5 fdump ?

greseofulvin
flucytosine
terbinafine
caspofungin
Click the card to flip 👆
1 / 15
Terms in this set (15)
what drug is a prodrug of 5 fdump ?

greseofulvin
flucytosine
terbinafine
caspofungin
flucytosine
What gives polyene membrane disrupters better activity and decreased toxicity?

A. A more basic amine
B. increased number of hydroxyl groups
C. LArger lactone ring
D. More conjugated double bonds
d
what class of drugs are all pro drugs?

A. nucleoside reverse transcriptase inhibitor inhibitors
B. HIV integrase inhibitors
C. HIV protease inhibitors
D. Azoles
A. nucleoside reverse transcriptase inhibitors

anything that mimics DNA bases has to be phosphorylated
What element does melaroprol contain

Cobalt
Arsenic
Silicon
Barium
Arsenic
What is required for the activity of HIV protease inhibitors

A. Transition state mimics
B. metabolism by CYP 2c19
C. binding under basic conditions
D. plasma protein binding
A. transition state mimics
What class of drugs inhibits CYPS

A. Azoles
B. polyene membrane disruptors
C. hiv integrase inhibitors
D. quinolines
Azoles
nifurtimox and tinidazoles mechanism of action are through the metabolism of what group

trifluoromethyl
allyl
ester
NITRO
Nitro
why is suramin sodium good for prophylaxis

A. short duration of action
B. does not accumulate in the plasma
C. can be give given PO
D. extensive plasma protein binding
D
resistance develops easily to atovaquone because it is present in what amount

A. high concentrations for a short period of time

B. High concentrations for a long period of time

C. low concentrations for a long period of time

D. low concentrations for a short period of time
C.

u dont wnat a low amount and u dont want a long duration of time
which compound would be an artemisinin

A
B
C
D
B
primaquine has a different mechanism of action from the other quinolines in that it generates reactive oxygen species through the metabolism of what gorup A. Ether B. amine C. piperaine D. cyanoBWhat is the tetrahydrofuran ring on posaconazole responsible for? Longer duration of action Tighter plasma protein biding increased cyp3a4 metabolism Wider spectrum of activityDnonnucleoside reverse transcriptase inhibitors cause hypersensitivity reactions through their reactions with what molecules FAD CYP GSH NADHC. GSHwhich compound is an allylamine A B C DDWhy can tipranavir be used in viruses that are resistant to other HIV protease inhibitors? A> not effluxed by P-gp B. Different mechanism of action C. taken into cells through endocytosis D. nonpeptidicNonpeptides the only one that is non peptide