Terms in this set (50)
Digoxin (Digitek, Lanozicaps, Lanoxin, Novodigoxin)
This drug is used when heart failure induces renal failure, or makes it worse. It improves ventricular contraction, increasing stroke volume and cardiac output.
Digoxin can cause severe ___________.
_________ prevent the absorption of Digoxin and may delay or inhibit effectiveness.
-Changes in color vision (more yellow color)
-Eyes sensitive to light
-Light flashes, or halos around bright lights
-Changes in behavior, mood, or mental ability
-Chest pain or palpitations
Manifestations of Digoxin toxicity include
Epoetin Alfa (Epogen, Procrit, EPO)
This drug prevents anemia by stimulating red blood cell growth and maturation in the bone marrow
Serious cardiovascular problems such as MI
Epoetin Alfa (Epogen, Procrit, EPO) can induce serious problems such as
INCREASED effect of Heparin
Side effects of Epoetin Alfa (Epogen, Procrit, EPO) include
It can raise H&H to the point that blood viscosity increases, raising blood pressure and increasing the risk for MI.
Drug dosage is reduce to prevent hemoglobin levels higher than 10-12 mg/dL
What levels can Epoetin Alfa (Epogen, Procrit, EPO) raise, and what does this cause?
Patients on Epoetin Alfa (Epogen, Procrit, EPO) must have hemoglobin monitored ________.
-Give subcut or IV
-Monitor labs (CBC, lytes, BUN, creatinine)
Nursing implications for Epoetin Alfa (Epogen, Procrit, EPO) include
Recombinant Human Erythropoietin
What type of drug is Epoetin Alfa (Epogen, Procrit, EPO)?
Aluminum hydroxide gel (Amphojel, AlternaGEL)
This drug lowers serum phosphate levels by binding phosphorus present in food in GI tract, neutralizing gastric acid, and inactivating pepsin.
What type of drug is Aluminum hydroxide gel (Amphojel, AlternaGEL)?
High blood phosphate levels cause hypocalcemia and osteodystrophy, therefore these drugs are needed to decrease serum phosphate levels and create balance.
Why are phosphate binders needed?
This drug binds phosphate in food, preventing its absorption.
Why is it important to teach patients to take Aluminum hydroxide gel (Amphojel, AlternaGEL) with meals?
(Aluminum hydroxide gel (Amphojel, AlternaGEL) reduces digoxin absorption and effects.)
ALSO AVOID giving with other oral meds (tetracycline, quinidine), and avoid alcohol, caffeine, and spices.
Aluminum hydroxide gel (Amphojel, AlternaGEL) should be separated from what other drug by
AT LEAST 2 HOURS
(Aluminum hydroxide gel (Amphojel, AlternaGEL) causes constipation and most pts with renal failure must reduce fluid intake, which also increases their risk for constipation.)
What other drug should patients take with Aluminum hydroxide gel (Amphojel, AlternaGEL)?
-Slow or irregular pulse
AE: Hypophosphatemia, GI obstruction with long-term use
Pts taking Aluminum hydroxide gel (Amphojel, AlternaGEL) must watch for signs of _________.
Sodium Polystyrene Sulfate (Kayexalate)
This drug promotes intestinal sodium absorption and potassium excretion
Cation Exchange Resin
What type of drug is Sodium Polystyrene Sulfate (Kayexalate)?
-Hypokalemia symptoms: ectopic beats, muscle twitches, weakness, ascending flaccid paralysis in distal to proximal direction involves the arms and legs, peripheral pulses difficult to palpate, paralytic ileus, abdominal distention, diarrhea
Side effects of Sodium Polystyrene Sulfate (Kayexalate) include
-Give orally or rectally
-If given via enema, retain for 30-60 minutes
Nursing implications for Sodium Polystyrene Sulfate (Kayexalate) include
Immunosuppressives (antilymphocyte, Immuran, monoclonal antibodies, mycophenolate, cyclosporin, interleukin2)
These drugs bind and suppress to prevent rejection and are used to prevent or treat transplant rejection
Side effects of Immunosuppressives (antilymphocyte, Immuran, monoclonal antibodies, mycophenolate, cyclosporin, interleukin2) include......
-S&S of infection
-Monitor renal and liver enzymes
-Monitor for signs of rejection post-transplant
-Proper precautions for being around other who have infections
Nursing implications for Immunosuppressives (antilymphocyte, Immuran, monoclonal antibodies, mycophenolate, cyclosporin, interleukin2) include.....
These drugs control hyperphosphatemia in end stage renal disease (ESRD) without promoting albumin absorption. Absorption from the GI tract requires vitamin D
Calcium Acetate (PhosLo)
Examples of calcium salts include
Hypercalcemia and renal calculi
Calcium Acetate (PhosLo) is contraindicated in
These foods may DECREASE the absorption of calcium supplements
-Monitor digoxin levels- hypercalcemia INCREASES the risk of cardiac toxicity
-Monitor phosphate levels
-Administer with meals
Nursing implications for pt receiving Calcium Acetate (PhosLo) include
This medication PREVENTS clot formation, but does not dissolve clots
This medication prevents and treats clot formation
The medication PREVENTS or SLOWS clotting
These drugs reduce the risk of MI, CVA, and clots associated with A-fib
Common anticoagulants are
Major side effect of anticoagulants is
-Monitor for bleeding
-Monitor blood levels
-Use soft toothbrush
-Monitor stools for blood
-Keep antidote handy (Vit. K)
-Dietary teaching- no leafy greens, liver, and fish
Nursing implications for pts on anticoagulants (Heparing, LMWH, Coumadin) include
These drugs are used to treat anticoagulant overdose
Major side effects of anticoagulant antagonists include
Vitamin K- binds to and neutralizes Coumadin
The antidote for Coumadin is
Protamine sulfate- binds to and neutralizes Heparin
The antidote for Heparin is
-Monitor lab values
-Monitor for clot formation
Nursing implications for pts on anticoagulant antagonists include
These drugs treat renal carcinoma by destroying cancerous cells
Interleukin-2, Interferon, Tumor necrosis factor
Common antineoplastic agents include
-Decreased urinary output
Side effects of antineoplastic agents (Interleukin-2, Interferon, Tumor necrosis factor) include
-Monitor lab values
Nursing implications for pts on antineoplastic agents (Interleukin-2, Interferon, Tumor necrosis factor) include
These are fast-acting anti-inflammatory drugs used to decrease inflammation and prevent tissue rejection
Decadron, Prednisone, Medrol
Common glucocorticoids include
-Fluid and electrolyte imbalances
-Oral fungal infections
-Throat irritation from inhalers
Side effects of glucocorticoids (Decadron, Prednisone, Medrol) include
-Eat food high in protein, calcium, and vitamin D
Nursing implications for pts taking glucocorticoids (Decadron, Prednisone, Medrol) include
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