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VET 226 Red Blood Cells (Exam #1)
Terms in this set (50)
"sugar coating" on some cells
What are the three functions of blood?
transport, regulatory, and defense
What does blood transport?
- carries O2
- waste products for disposal
- WBC's to infection sites
How does blood help regulate the body?
- maintain body temperature
- homeostatic fluid maintenance
- pH regulation
What is the normal pH range of blood?
7.35 - 7.45
Blood is normally slightly (acidic/alkaline)
What blood cells help with the bodies defense system?
WBC's and platelets
Whole blood consists of ...
plasma and all cellular components
Blood in the vessels that is carried to and from heart and lungs
This is the fluid portion of blood (93% water)
What is the average PCV for dogs?
What is the average PCV for cats?
What are the two most predominant plasma proteins?
Albumin and globulin
This element is essential to clotting processes and is found in plasma
(true/false) Fibrinogen is not found in serum. Why or why not?
True; it is used up when blood is clotted
Protein molecule that is the functional part of an erythrocyte (carries oxygen)
What are the two parts of hemoglobin and what do they contain?
1. Heme- contains iron
2. Globin- contains amino acids
The thinnest area of an erythrocyte that contains decreased amounts of hemoglobin
Found in the blood during liver damage and causes a yellow color known as icteric
The production of all blood cells
A fetus produces RBC's in the ________ and _________
liver and spleen
What organ can assist with RBC production if needed and can store excess blood?
When determining blood volume, use the animal's _________ body weight
What is the equation for determining blood volume?
50-100ml/kg of lean body weight (avg. 75ml)
This is produced by the kidney in response to hypoxia
Intravascular hemolysis is responsible for _______ of RBC destruction
What is the lifespan of a dogs RBC?
What is the lifespan of a cats RBC?
What is the RBC lifespan for horses and sheep?
What is the RBC lifespan for mice?
With regenerative anemia, small animals will regenerate erythrocytes in ___to ___ days
With hemolytic anemia, erythrocyte destruction takes place where?
within the blood
What is polycythemia and what is it caused by?
1. an increase in total cell mass of blood due to fluid loss
2. Caused by:
- reduced water consumption
Variation in size of an erythrocyte
(true/false) Cats generally have smaller RBC's than dogs
(true/false) Avians and reptiles have nucleated RBC's
What is Post-prandial lipemia?
cloudy change in plasma following a meal due to suspension of fat in the plasma
What should heparin be used for? What should it not be used for?
Heparin is ideal for blood chemistries but should not be used to make differential slides (interferes with WBC staining)
EDTA is ideal for hematologic studies because it does not interfere with ____________ ________
Immature RBC's that contain organelles
Cats have 2 morphologic forms of reticulocytes, what are they? Which ones do we count?
1. Aggregate form- large clumps ( ONLY COUNT THESE)
2. Punctate form- 2-8 small, singular, basophilic granules
What percent of the total RBC mass is replace every day?
The entire blood supply is replaced approx. every _________
When making a blood film, the 2nd slide should be placed at what angle?
When reading a blood film, what area do we look at?
inspect the monolayer just past the "feathered edge"
Average size of erythrocytes
mean corpuscular volume (MCV)
mean weight of hemoglobin contained in the average erythrocyte
mean corpuscular hemoglobin (MCH)
concentration of hemoglobin in the average erythrocyte
mean corpuscular hemoglobin concentration (MCHC)
What is the equation to estimate hemoglobin?
PCV/ 3= ____ g/dL
What is the equation for RBC count?
PCV/6= ___ mil/microliter
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