Upgrade to remove ads
Only $35.99/year

Pharm Week 8 Quiz: inflammatory and immune

Terms in this set (18)

glucocorticoid dosage
-highly individualized
-determined empirically (trial and error)
-start low, go slow
-smallest amount that is effective
-increase during times of stress
-wean gradually***
cycloooxygenase (COX)
COX 1= good cox
-protects GI mucosa
-promotes vasodilation
-promotes platelet aggregation
-supports renal function
COX 2= bad COX
-promotes inflammation
-promotes pain
-promotes fever
-contributes to colon cancer
cyclooxyrgenase uses
-supress inflammation
-relieve pain
-reduce fever
cyclooxyrgenase adverse effects
-gastric ulceration
-bleeding
-renal impairment
-COX 2- promotion of MI/stroke
first generation NSAIDs
-used to treat inflammatory disorders (osteoporosis, rheumatoid arthritis)
-relieve dysmenorrhea
-suppress fever
dysmenorrhea
menstrual cramps
adverse effects of aspirin
-GI effects
-bleeding
-renal impairment
-reye's syndrome
-bleeding during pregnancy
-hypersensitivity reaction
reye's syndrome
-rare condition that commonly affect recovering from a viral infection that causes swelling of the liver and brain (aspirin)
what aspirin helps with
-antiinflammaory
-anti pain
-anti pyretic
-anti platelet aggregation
Nonapirin First generation NSAIDs
-inhibit COX 1 and COX
-inhibition i reversible unlike aspirin
second generation NSAIDs
-COX 2 inhibitors
-increase risk for MI and stroke
celecoxib (celebrex) adverse effects and drug interactions
AE:
-abdominal pain
-GI ulcers
-cardiovascular events
-renal impairment
DI:
-warfarin
acetaminophen (tylenol)
-treatment for overdose: acetylcysteine (mucomyst, acetadote)
severe allergic reaction responses
-epinepherine is drug of choice
first generation (sedating)
- benadryl (diphenhydramine)
second generation (non-sedating)
fexofenadine (allegra)
*cetirizine (zyrtec)*
loratadine (claratin)
desloatadine (clarinex)
cyclosporine (cytoxan)
-increases risk for infection due to neutropenia
- drug of choice for organ rejection
immunization
builds up antibodies
Sets with similar terms