Pharm 3 - PD and AD

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What is the cornerstone treatment for PD?
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Terms in this set (30)
What is the cornerstone treatment for PD?
Levodopa/carbidopa
Which Parkinson's disease drug improves all symptoms of PD, particularly bradykinesia and rigidity?
Levodopa/carbidopa
Brand name for levodopa/carbidopa:
Sinemet®
Nausea and vomiting, anorexia, hypotension, anxiety, obsessive compulsive behavior, psychoses, hallucinations and paranoia are side effects of what Parkinson's disease drug?
Levodopa/carbidopa
Dyskinesias and motor fluctuations are long-term side effects of what PD drug?
Levodopa/carbidopa
What dopamine receptor agonists are used to treat Parkinson's disease?
Pramipexole (Mirapex®)
Ropinirole (Requip®)
What PD drug is used in late PD to lower L-dopa uses and minimize dyskinesias and motor fluctuations?
Pramipexole (Mirapex®)
Ropinerole (Requip®)
Requip®
Use of these PD drugs can lead to overstimulation and cognitive impairment and dizziness and sedation are noted with higher doses.
Pramipexole (Mirapex®)
Ropinerole (Requip®)
Requip®
Pramipexole (Mirapex®) is used for:
Late PD to minimize dyskinesias and motor fluctuations
Ropinerole (Requip®) is used for:
Late PD to minimize dyskinesias and motor fluctuations
Side effects of Requip®:Overstimulation, cognitive impairment, dizziness and sedationSide effects of pramipexole (Mirapex®)overstimulation, cognitive impairment, dizziness and sedationWhat Parkinson's disease drugs are used to improve motor functions and ADLs and may help with reducing L-dopa withdrawal?Selegiline (Eidepryl®) Rasagiline (Azilect®)Selegiline (Eidepryl®) is used for:Improve motor functions and ADLs in patients with PD; help with L-dopa withdrawalsRasagiline (Azilect®) is used for:Improve motor functions and ADLs in patients with patients; help with L-dopa withdrawalsCNS disturbances in older patients, increased side effects when taken with L-dopa agonists, and excitability and insomnia are side effects of what PD drugs?Selegiline (Eidepryl®) Rasagiline (Azilect®)When should you take selegiline (Eidepryl®) or rasagiline (Azilect®)?in the morning due to its amephetamine metabolite effect - excitability and insomniaWhat PD drugs should not be taken with selegiline (Eidepryl®) or rasagiline (Azilect®)?TCAs and SSRIsWhat Parkinson's disease drug is given with dopamine agonist (Mirapex® and Requip®)?entacapone (Comtan®)What PD drug can trigger dyskinesias or produce cognitive impairment, and has similar side effects to dopamine agonists like pramipexole and ropinirole?entacapone (Comtan®)What PD drug has a concern on liver toxicity?entacapone (Comtan®)Which PD drug is originally used for influenza but can also be used with mild tremors rather than rigidity?Amantadine (Symmetrel®)Nausea, insomnia, hallucinations, and autonomic symptoms are side effects of what Parkinson's disease drug?amantadine (Symmetrel®)Donepizil (Aricept®) and Rivastigimine are drugs that treat?Alzheimer's Disease; cholinersterase inhibitorsWhat are side effects of Donepizil and Rivastigimine?N/V, diarrhea, bradycardia, sleep disturbances, weight lossA patient with Alzheimer's disease is experiencing nausea, diarrhea, bradycardia, and weight loss? What drug may be causing these side effects?Aricept® RivastigimineMemantine (Namenda) is what drug?Alzheimer's Disease; NDMA antagonistWhat side effect is associated with memantine (Namenda)?AgitationA patient with Alzheimer's disease is showing signs of agitation after starting her new medication. What drug do you think is affecting her new behavior?memantine (Namenda)Is there a cure for Alzheimer's?no