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Microbiology Jeopardy Exam 4
Terms in this set (25)
Which is true of an attentuated strain of a pathogenic microbe infecting a susceptible healthy host?
The microbe will replicate in the host but not cause disease.
In order to cause disease, successful infectious pathogens must be able to do all of the following except:
kill the host
Pathogens that have the ability to change their surface antigens are better able to do which of the following?
evade host defenses (African sleeping sickness and gonnorhea)
Which of these outcomes is the focus of molecular Koch's postulates?
the identification of virulence factor genes
Pathogenic E.coli O157:H7 evolved from a non-pathogenic strain as a result of this genetic change?
the acquisition of virulence genes from Shigella
Which of these results in immunological memory?
the adaptive immune response
Which of the following is not a nonspecific natural defense barrier against microbial invasion?
antibodies produced from B lymphocytes
A component often added to vaccines to enhance the immune response to microbial components in the vaccine?
What is the effector function of CD8+ cells?
the cytotoxic killing of infected cells
Exogenous antigen is usually taken up by the antigen-presenting cells through phagocytosis, processed, and presented to T cells on their surface by these?
All of the following are examples of how virulence factors facilitate establishment of disease by a pathogen except:
Which of these virulence factors is not possessed by the pathogen Neisseria gonorrhoeae?
production of urease
Which component of lipopolysaccharide (LPS) is responsible for inducing a strong inflammatory response?
The DTaP vaccine is designed to protect against which diseases?
diphtheria, tetanus, and pertussis
A person who has strep should always be treated with antibiotics to reduce the risk of sequelae. What are the two most common sequelae?
glomerulonephritis and rheumatic fever
What is an example of a zoonotic virus?
Rhinovirus is a cause of the common cold. what type of infection does it usually cause?
The human immunodeficiency virus (HIV) can be transmitted by all of the following mechanisms except:
through a mosquito bite
Many viral infected cells will undergo apoptosis and die. Why is this important for the organism as a whole?
It limits the production of new viruses by the cell
The papillomavirus infects keratinocytes that are not actively dividing. What does this virus do to gain nucleotides to support viral replication?
It stimulates the cell to enter into the "S-phase" of the cell cycle
The mode of action of beta-lactam antibiotics in bacteria is directed against:
peptidoglycan synthesis (G+ bacteria)
Attentuated vaccines are generally more effective than subunit vaccines because ?
attenuated vaccines may permit viral growth with enhanced disease mimicry
Acyclovir is a commonly used anti-herpes drug. It is a structural analog of dideoxyguanine. You would expect this drug to interfere with:
viral DNA replication
The original polio vaccine was developed by Jonas Salk in 1952 was a _____ vaccine?
This virus family led to the identification of proto-oncogenes:
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