How can we help?

You can also find more resources in our Help Center.

62 terms

RED BLOOD CELLS

RBC and Platelet maturation,Morphology, inclusions and Anemia
STUDY
PLAY
Erthropoietin
hormone secreted by kidneys for the formation of RBCs---- released during anermia
Splenic contraction
significant, allows horses to have more speed, rbc stored here, circulate in spleen, caue fight or flight response, RBC can be damaged here
RBC function
transports O2 from the lungs to the tissues and carbon dioxide from tissues to lungs
hemoglobin
iron-containing protein in red blood cells that carries oxygen for delivery to cells
methemoglobin
An altered hemoglobin which does not carry oxygen.before the liver can convert back to hemoglobin
MCV
Mean corpuscular volume average volume of RBCs; useful for anemia classification
MCH
mean corpuscular hemoglobin
MCHC
mean corpuscular hemoglobin concentration
erythropoiesis
the process of producing red blood cells by the stem cells in the bone marrow
Rubriblasts
Step 1 large solid nucleus w/ little cyto (stains guite dark), for every stem cell, there is one of these cells, split into 2 prorubricytes
Prorubricyte
Step 2 : 2 cells form from the division of a rubriblast (cell size dec., nucleus size decreases, (cytoplasam matures and becomes lighter) has to end up w/ no nucleus
Rubricyte
Step 3. in RBC pathway. Cell undergoes 3 mitotic divisions. Cell size decreases, nuclear size decreases, and cytoplasm matures.
Metarubricyte
Step 4. and contains a very dense nucleus (nRBC)
57%-67%
What percent in a dz animal where there be metarubricytes?
Erythrocyte
a mature blood cell that contains hemoglobin to carry oxygen to the bodily tissues
Platelets
thrombocytes; cell fragments in the blood essential for blood clotting (coagulation)
Megakaryoblasts
build mature plateletes
Anisocytosis
Unequal sized RBC's
polychromasia
condition of many colors; clinically means erythrocytes with varies or multicolored staining qualities
hypochromasia
No color in cell due to inuffeicient Hb with in the cell. Low Iron.
Discocyte
Biconcave Disc, normal RBC
Normocytic
A normal sized Erythrocyte....
normochromic
pertaining to normal concentration of hemoglobin (colour)
Microcytosis
Small RBC's, anemia's with decreased MCV, observed normal in Asian dogs
Macrocytosis
A condition anemia where there is interference with nucleic acid synthesis inhibiting cell division (vitamin B12 / folic acid def)min. poodles and malamutes and the cell is bigger.
hypochromasia
red blood cells that have a decreased red color, iron deficiency, lead toxicity
polychromasia
condition of many colors; clinically means erythrocytes with varies or multicolored staining qualities
poikilocytosis
abnormal variations in the shapes of RBC (poikilo 5 variation)
codocytes
aka target cells associated with liver dz, and anemia
stomatocytes
malamutes, min. schnauzers, artifact
Eccentrocytes or torocytes
Shifting of Hb to one side of the cell, resulting in a clear zone outlined by membrane
ovalocyte
shaped like an oval membrane defect
dacryocyte
tear drop cell - fragmentation disease
Schistocytes
Fragmented of a RBC, DIC!!!!,CHF DEATH IS COMING
acanthocytes
RBC's w/ rounded projections (irregular borders) seen in pigs
echinocyte
abnormal red blood cell with a burr (spiny) appearance. Artifacts due to Creanation in smear.
spherocytes
Spher chaped . Microcytic, hyperchromic, associated with autoimmune hemoltic anemia.AIHA
Burr cells
Renal Dz and lipidosis elongated echinocytes
Ghost cells
remnant of cell membrane. no hemoglobin
agglutination
clumping of blood cells
anemia
a deficiency of red blood cells
anemia
polychromasia,reticulocytosis,anisocytosis ,nRBC,Howell-jolly bodies are signs of this condition.
basophilic stippling
What is the term for cytoplasmic remnants of RNA in RBCs, seen in lead poisoning?
Relative
Dehydration, red blood count the same for pcv is what kind of polycythemia?
Primary
myeloprolifirative disorder, production of too many red blood cells by the BONE MOARROW,is what kind of polycythemia?
2nd
REDUCED O2, increased erythropoeitin levels.HR DZ, pneumonia. and renal dz is what kind of polycythemia?
Polychromatiphil
They are reticulocytes when stained with new methylene blue
Lead Poisoning
This erythrogram would include basophilic stippling with marked nRBC's and minimal polychromasia.
polycythemia
an excessive or abnormal increase in the number of erythrocytes
Eosinophilic
As a erythrocyte matures, the cytoplasm changes color from basophilic to what?
megakaryocyte
The only cell to become larger as it matures.
Aggregate
When counting retic's in cats, we only count what on the reticulocytes?
Echinocyte
Crenation is a type of Echinocyte.
Schistocyte
A RBC fragment is called what?
Rouleaux
RBC abnormality characterized by coin like stacks
Agglutination
Abnormality that is characterized by grape like clusters of RBC's that due not break up when diluted.
Cat
Who has the shorter RBC life span Dog or Cat?
Renal Failure
The lowest circulating erythropeoitin concentration would be found in animals with what type of chronic problem
Compensatory
Tachycardia,Tachypnea, splenic contraction, and movement of interstitial fluid to the vascular space are all what kind of mechanism.
Agglutination
This would be indicative of immune-mediated hemolysis.
PCV
A low blood to aticoagulant ratio would cause a false reading in what?
Heinz bodies
Precipitated denatured hemoglobin in red cells may be referred to what?