In the Michaelis-Menten kinetics what do the following mean:
Km
Vmax

Draw a typical hyperbolic curve on a Michaelis-Menten Plot, then draw how the addition of a competitive and non-competitive inhibitor would change the kinetics of the reaction.

In the Michaelis-Menten kinetics what do the following mean:

Km:
- the concentration of substrate at 1/2 Vmax
- this is INVERSELY related to the affinity of enzyme for its substrate

Vmax:
- maximal velocity at which enzymatic reaction occurs
- is directly proportional to the enzyme concentration

Competitive inhibitor: would raise Km but Vmax is the same

Non-competitive inhibitor: would lower Vmax?