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Explain why these structures are found only in the structure of eukaryotic chromosomes and not in the chromosome found in prokaryotes
Eukaryotic chromosomes help package the DNA into smaller pieces. Prokaryotes don't have histones and have to use supercoiling
Outline how nucleosomes help regulate transcription
•Supercoiling condenses the DNA molecule by a factor of x15,000
•Histones are responsible for the packaging of DNA
•The metaphase chromosome is an adaptation for mitosis and meiosis
•The fibre must be less condensed for transcription to occur during the interphase
•Condensing controls if the genes are transcribed or not
A mutation that changes an amino acid codon to one of the three stop codons, resulting in a shorter and usually nonfunctional protein
Short, highly repeated eukaryotic DNA sequences, usually clustered in heterochromatin and generally not transcribed
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