PATHO EXAM 2

intracellular fluid (ICF)
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Terms in this set (22)
intracellular fluid (ICF)
2/3 of body fluid located in the cell
extracellular fluid (ECF)
1/3 of body fluid located outside the cell
intake 1400-1800 ml drinking
output 1400-1800 ml of urine
intake 700-1000 ml food
output 100 ml stool
intake 300-400 ml oxidation
output 300-500 ml (insensible water loss)
total intake & output
2400-3200 ml
hydrostatic pressure
pushes water out
osmotic (oncotic) pressure
pulls water back
net filtration
the movement of fluid back and forth across the capillary walls
starling forces
another word for net filtration
capillary hydrostatic pressurethe movement of fluid out of the arteriolar end of the capillary and into the interstitial spacecapillary oncotic pressure(from plasma proteins); at the venous end, it attracts water back into the vascular spaceinterstitial hydrostatic pressurethe movement of fluid and proteins from the interstitial space into the capillary (lymphatics)interstitial oncotic (osmotic) pressurethe movement of fluid from the capillary into the interstitial spacenormal ICF/ECF osmotic pressures280 to 294 mOsm; water is equally distributed between the interstitial fluid and intracellular compartmentsosmotic forces: Na+ECF osmotic force; more responsive to changes in osmolality than ICFosmotic forces: K+ICF osmotic forceADH (antidiuretic hormone) secreted in response toincreased plasma osmolality, decreased blood volume, or decreased blood pressureosmoreceptors in hypothalamus stimulated byincreasing osmolality, causing thirstvolume sensitive receptors (R+L atria, thoracic vessels) & barorecptors (aorta, PA, and carotid sinus)stimulate ADH releaseedemaexcessive fluid accumulation in the interstitial spacesedema caused byincreased capillary hydrostatic pressure - due to venous obstruction, Na+ and H20 retention, thrombophlebitis, hepatic obstruction, restrictive clothing, prolonged standing lowered plasma oncotic pressure - due to liver disease, protein calorie malnutrition, kidney disease, excess wound drainage, burns increased capillary membrane permeability - trauma, burns, neoplasm, allergic reactions lymphatic channel obstruction - blocked lymphatic channels lead to lymphedema