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Cytoskeleton & cell attachment

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tight junction

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Terms in this set (39)

also called: occluding junction

composed of: claudin &occludin

makes "belt" around cell, prevents molecules from leaking through sheet

adherens junction

also called zonula adherens, "belt" desmosome

adherens junction

composed of: cadherins

adherens junction

use alpha- and beta-catenin to link to actin cytoskeleton of cell

adherens junction

need high Ca2+ for "zippering" / attachment

anchoring junctions

allow attachment between cells and of cell to extracellular matrix

anchoring junctions

adherens junction, focal adhesion, desmosome, hemidesmosome

allows cell to attach to ECM: integrin binds to ECM proteins via fibronectin and to cytoskeletal actin via talin

protein family that forms focal adhesions and hemidesmosomes - used for cell-matrix binding

binds integrins of focal adhesions to ECM

binds integrins to actin or intermediate filaments in cytoskeleton

forms adherens junctions and desmosomes when triggered by high levels of Ca2+; single-pass transmembrane proteins

communicating junctions

mediate passage of chemical or electrical signals from one interacting cell to its partner