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Terms in this set (17)
What are the three types of hyper adrenal syndromes?
(1) Cushing syndrome (2) Hyperaldosteronism (3) Adrenogenital (virilizing) syndromes
Cushing syndrome is caused by any condition that causes elevated _____ levels.
What is the most common cause of cushing syndrome?
Exogenous glucocorticoids (iatrogenic cushing syndrome)
Endogenous causes of Cushing syndrome can be divided into _____ and _____ types.
ACTH dependent, ACTH independent
Adrenocorticotropic hormone (ACTH) acts on the adrenal cortex to cause the release of _____.
Corticosteroids (e.g. cortisol)
What hormone acts on the adrenal cortex to cause the release of corticosteroids (e.g. cortisol)?
Adrenocorticotropic hormone (ACTH)
What is the most common cause of endogenous cushing syndrome?
What is the most common cause of ACTH-dependent cushing syndrome?
What is the most common cause of ACTH-independent cushing syndrome?
_____ is a disease associated with prolonged exposure to inappropriately high levels of the hormone cortisol.
In term of nonpituitary tumors, what type is most commonly responsible for the secretion of ACTH?
Small cell carcinoma of the lung
_____ and _____ are the two most common causes of ACTH independent cushing syndrome.
Adrenal adenoma, Adrenal carcinoma
True or False: Cushing syndrome due to exogenous glucorticoids, suppression of ACTH (via negative feedback affect) results in unilateral cortical atrophy.
False, cushing syndrome due to exogenous glucorticoids, suppression of ACTH (via negative feedback affect) results in BIlateral cortical atrophy.
Diffuse adrenal cortical hyperplasia is seen in individuals with what type of cushing syndrome?
What are the six clinical findings associated with cushings syndrome?
(1) Rapid weight gain/inability to lose weight (2) Moon facies (3) Dorsocervical fat pad (Buffalo hump) (4) Hirsutism and irregular menses in women (5) Glucose intolerance/type 2 diabetes (6) Low bone mineral density/osteoporosis
Which of the following is NOT associated with the clinical course of cushing syndrome? A) Atrophy of fast twitch myofibers leading to weakness B) Secondary diabetes C) Thick, tough skin D) Osteoporosis E) Poor wound healing
C) Thick, tough skin
Which of the following is NOT associated with the clinical course of cushing syndrome? A) Menstral abnormalites B) Thin, fragile skin C) Infections D) Mental disturbances E) Conn syndrome
E) Conn syndrome