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4 - Microbe factors
Terms in this set (11)
This factor of GAS inhibits phagocytosis and activation of complement, is cytotoxic to neutrophils in serum and mediates bacterial attachment.
This factor of GAS lyses erythrocytes and PMNs, and is responsible for the production of Abs that are tested in detecting this bug.
This factor is an extracellular ENZ that depolymerizes viscous DNA in pus and disintegrates PMNs, allowing Strep to move more freely in tissue
This factor is an extracellular ENZ that catalyzes plasminogen --> plasmin, resulting in fibrin digestion and facilitating the spread of Strep in tissue.
This factor for GAS stimulates type-specific humoral immunity
This toxin activates large numbers of Th cells, interacting with MHCs on APC and variable region of TCRs --> nonspecific T cell activation, and release of IL-2 from T cells and IL-1 and TNF from macrophages.
TSST, a superantigen from Staph aureus
These factors (x3) cause capillary leakage, circulatory collapse, hypotension, shock, fever, erythroderma, and multiorgan failure
IL-2 (T cells) IL-1 and TNF (macrophages) in Toxic Shock syndrome
These three toxins are those that have super antigen activity
Enterotoxins, Exfoliative toxins, and TSST-1
This bug produces urease
Inhibits Ach release
Inhibits Glycine and GABA release
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