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EXAM 4: Depression and Anxiety
Terms in this set (19)
Four regions of the brain associated with depression:
Prefrontal cortex, amygdala, thalamus, hippocampus
___ is associated with fear, arousal, stress, formation of memories of emotional events
___ is associated with executive functioning of the brain, discrimination between conflicting thoughts, planning complex cognitive behaviors, working toward a goal
One function of the prefrontal cortex is is to ___, to allow the individual to focus on tasks
inhibit the amygdala
Depressed individuals have ___ activity of the amygdala
Depressed individuals have ___ activity of the prefrontal cortex
___ is associated with spatial orientation and long-term memory
___ receives filtered sensory information via the reticular activating system and relays it to the cerebral cortex. Also plays a significant role in arousal, wakefulness and alertness.
Depressed individuals have ___ activity of the lateral habenula
Initially after starting SSRI treatment, serotonin autoreceptors will ___ the release of serotonin
With chronic SSRI treatment, some serotonin autoreceptors are internalized by the midbrain raphe nuclei. This permits ___ firing by the presynaptic neuron and ___ release of serotonin into the synaptic cleft
___ is involved in synaptic plasticity and neurogenesis
Depressed individuals have ___ BDNF levels
The short variant of the SLC6A4/5-HTTLPR leads to ___ SERT production
The ___ variant of the SLC6A4/5-HTTLPR is associated with depression
The short variant of the SLC6A4/5-HTTLPR is associated with increased ___ activation
Environmental stress and adverse childhood events lead to what epigenetic change that can lead to depression?
Increased or decreased glutamate activity is associated with depression?
Cognitive behavioral therapy increase activity of the ___
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