Terms in this set (16)
Name the FIVE main types of thyroid carcinoma and their relative percentages
1. Papillary carcinoma: 80% (Popular Papillary)
2. Follicular carcinoma: 10%
3. Medullary carcinoma: 5%
4. Hürthle cell carcinoma: 4%
5. Anaplastic/undifferentiated carcinoma: 1% to 2%
What are the signs/ symptoms?
Mass/nodule, lymphadenopathy; most are euthyroid
What comprises the workup?
FNA, thyroid U/S, TSH, calcium level, CXR, scintiscan 123
What oncogenes are associated with thyroid cancers?
Ras gene family and RET proto-oncogene
What is papillary carcinoma's claim to fame?
Most common thyroid cancer (Think: Papillary Popular) 80% of all thyroid cancers
What is the environmental risk?
What is the average age?
What is the sex distribution?
Female male; 2:1
What are the associated histologic findings?
Psammoma bodies (Remember, P Psammoma Papillary)
Describe the route and rate of spread
Most spread via lymphatics (cervical adenopathy); spread occurs slowly
131 I uptake?
What is the 10-year survival rate?
What is the treatment for: < 1.5 cm and no history of neck radiation exposure?
Options: 1. Thyroid lobectomy and isthmectomy 2. Near-total thyroidectomy 3. Total thyroidectomy
> 1.5 cm, bilateral, cervical node metastasis OR a history of radiation exposure?
What is the treatment for: Lateral palpable cervical lymph nodes?
Selective neck dissection (ipsilateral)
What postoperative medication should be administered?
Thyroid hormone replacement, to suppress TSH
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