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The study of drugs, their actions on living organisms, and how they affect the body cells
What 4 things do we need to know about the Pt?
study of time req. for absorption durtaion and action&effect, distribution in body and method of excretion
4 Drug Names
Chemical Name- chemical make up
Generic Name-before drug is approved
Offical name-given by USP often same as Gen.
Brand name-Trade name given by manufact..
Examples of the 4 Drug names
Brand- Bufferin, Excedrin, Bayer, St. Josephs
blood brain barrier
-fat soluble meds get through but H20 doesnt
-antibiotics have difficulty
-not very selective about what crosses
OA variations of H20 and fat:
lower water= doesn't distribute as well
higher fat= longer duration of drug action
slower drug distribution
lower weight means higher Cnx
Agonist- same response as physiologic/ endogenous substance
Antagonist- inhibits cell function by occupying receptor sites
when meds change into less active or inactive form, as related to the metabolism
Effects to Drugs
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