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What is 1 + 3?
The study of drugs, their actions on living organisms, and how they affect the body cells
What is the most important goal of pharmacology?
The safe and accurate administration of meds
What 4 things do we need to know about the Pt?
Use of drugs to treat, cure, relieve, or prevent disease
Process by which drug changes body
study of time req. for absorption durtaion and action&effect, distribution in body and method of excretion
4 Drug Names
Chemical Name- chemical make up
Generic Name-before drug is approved
Offical name-given by USP often same as Gen.
Brand name-Trade name given by manufact..
Examples of the 4 Drug names
Brand- Bufferin, Excedrin, Bayer, St. Josephs
Drugs are classified how?
Aspirin is classified how-
Absorption (p 839)
Route of Administration
Nurse cant change independently
Acidity or Alkalinity
Acid- stomach absorbs well
Base- better absorbed in intestines
Distribution can be affected by:
H20 and fat
blood brain barrier
-fat soluble meds get through but H20 doesnt
-antibiotics have difficulty
-not very selective about what crosses
agent or factor that causes malformation of embryo
OA variations of H20 and fat:
lower water= doesn't distribute as well
higher fat= longer duration of drug action
slower drug distribution
lower weight means higher Cnx
Agonist- same response as physiologic/ endogenous substance
Antagonist- inhibits cell function by occupying receptor sites
binds to many drugs making them ineffective
when meds change into less active or inactive form, as related to the metabolism
Main organs of Excretion:
1* = Kidneys
2*= bowel, lungs,
exocrine glands- breast sweat
Give 2 examples of pharmacodynamics
Insulin, or synthetic thyroid hormone
Effects to Drugs
Mild Allergic reaction
Uticaria- raised irregularly shaped lesion
Rash- small raised vesicles
Pruritus- itching of skin
Rhinitis-inflammation of mucus membrane of nose
Lacrimal Tearing- excessive tearing