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lecture 3- intro to dosage forms
Terms in this set (43)
What are differ sources of drug?
(a drug is rarely administered in original form)
What does API stand for?
Active Pharmaceutical Ingredient
Why are dosage forms important?
-because API handling & dosing can be difficult
-enhances the stability of API in the external environment
-protects the API degradation @ the site of administration
-help w/ unpleasant tastes/odor
what are the desirable properties of dosage form?
-convenient to handle, use, and store
-not disrupt the pharmacological activity of drug
-protect the drug substance
What are the physical states of dosage forms?
what are examples of solid dosage forms?
what are examples of liquid dosage forms?
what are examples of semisolid dosage forms?
what is an example of gaseous dosage form?
advantages of solid dosage form?
-easy to carry & transport
-easy to administer
-available in differ strengths
disadvantages of solid dosage forms?
-difficulty to swallow
-delay in the onset of action
Advantages of liquid dosage forms
-effective more quickly than solids
-easier to swallow
-reconstituted lyophilized powders (easy to place in feeding tube or injection)
-flexible in dosing
disadvantages of liquid dosage forms?
-bulky (high cost of transportation)
-stability is an issue
-need an accurate device to measure
-unpleasant tastes & odors
advantages of semisolid dosage forms?
-easy to apply on skin
-could be used for both topical and systemic delivery
-emollient (smoothing) action can be achieved
-can be compounded extemporaneously (w/o preparation)
disadvantages of semisolid dosage forms?
-pastes are not suitable for application to hairy areas
-occlusive (prevents the flow of air)
-difficult to remove
-incorporation of certain drugs is a bit challenging
-stability: phase separation
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