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4 Genome

Terms in this set (29)

The human genome has __ pairs of chromosomes and a pair of sex chromosomes
22
A transposition
is when one piece of of a chromosome becomes attached to another.
ex. abnormal chromosome 12 has a piece of #4 attached, causing ataxia
If the two genomically different species interbreed...
mitotic divisions may generate a viable adult, but the hybrid species will be sterile due to meiotic failure.
ex. muntjac
_____________ are basic units of DNA organization
they are made up of 2 molecules each of H2A,H2B, H3,H4, wrapped by DNa and helf together by H1 protein
Nucleosome includes ____ nucleotide pairs of DNA in a "beads on a string format"
~200
Micrococal Nuclease digests ____ ___ . ______________ is protected from nuclease digestion
linker DNA, DNA w/ histone cores
The condensed chromosome is the ____ level of DNA organization.
highest
DNA is at its maximum condenstation state during _____________
metaphase
During ___________ most DNA is decondensed
interphase
Heterochromatin
remains condensed in interphase
The drosophilia _____ _____ is necessary for normal eye pigmentation
white gene. A translocation of this gene will not allow expression
An inacctivated X chromosome is called
Barr body
During early stages of development, what happens to X chromosomes?
In the cells, one X chromosome (Xm, Xp) is randomly chosen and deactivated.
Ex. Calico, Tortoiseshell cats
Gene
a segment of DNA that is transcribed and codes for a functional product: polypeptide or RNA
Exons
coding sequence within genes
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