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19 terms

skeletal terms

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Acute gouty arthritis
condition where uric acid crytals accumulate in the joints of the big toes, ankles, wrists, fingers, knees, or elbows, resulting in red, swollen, or inflammed tissue
Autoantibodies
proteins called rheumatoid factors released by B lymphocytes that tear down the body's own tissue
Azotemia
accumulation of nitrogenous waste products in the kidneys that can result in death if untreated
Bisphosphonates
class of drugs that block bone resorption by inhibiting osteoclast activity
Bone deposition
opposite of bone resorption; the process of depositing mineral components into bone
Bone resorption
process of bone demineralization or the breaking down of bone into mineral components
Calcifediol
substance formed in the first step of vitamin D formation
Calcitonin
hormone secreted by the thyroid gland that increases the deposition of calcium in bone
Calcitriol
substance that is transformed in the kidneys during the second step of the conversion of vitamin D to its active form
Cholecalciferol
vitamin D3 formed in the skin by exposure to UV light
Disease-modifying antirheumatic drug (DMARD)
drugs from several classes that modify the progression of rheumatoid arthritis; include hydroxychloroquine (Plaquenil), methotrexate (Rheumatrex), or sulfasalazine (Azulfidine)
Gout
metabolic disorder characterized by the accumulation of uric acid in the bloodstream or joint cavities
Hyperuricemia
an elevated blood level of uric acid, which causes gout
Osteoarthritis
disorder characterized by degeneration of joints, particularly the fingers, spine, hips, and knees
Osteomalacia
rickets in children; caused by vitamin D deficiency characterized by softening of the bones without alteration of basic bone structure
Osteoporosis
condition in which bones lose mass and become brittle and susceptible to fracture
Paget's disease
disorder of bone formation and resorption characterized by weak, enlarged, and deformed bones
Rheumatoid arthritis
systemic autoimmune disorder characterized by inflammation of multiple joints
Selective estrogen receptor modulator (SERM)
drug that produces an action similar to estrogen in body tissues; used for the treatment of osteroporosis in postmenopausal women