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Chapter 08: Antifungal and Antiviral Agents
Terms in this set (29)
The mechanism of action of nystatin involves binding to:
Sterols in the fungal cell membrane
Which of the following agents has poor oral absorption?
Nystatin is used for both the treatment and the prevention of __________ in susceptible cases.
An aqueous suspension of nystatin should remain in the mouth for __________ for the best effect.
The main advantage of nystatin pastilles over the aqueous suspension is that:
15 minutes are required for the lozenge to dissolve in the mouth
Which of the following statements is true concerning clotrimazole?
Systemic clotrimazole has been assigned to U.S. Food and Drug Administration (FDA) pregnancy category C
Requires and acidic environment for adequate systemic absorption
The primary route of excretion for ketoconazole is:
The most serious adverse reaction associated with ketoconazole is:
Gynecomastia is an adverse effect that is specific to
The following statements are true of ketoconazole except one. Which one is the exception?
It has masculinizing effect by increasing testosterone levels
Ketoconazole should not be used with __________ because it renders the blood level of ketoconazole undetectable.
All of the following antifungal agents are useful in dentistry except:
Which of the following is the first antifungal agent to be effective in the treatment of onychomycosis of the toenail or fingernail?
Which agent, when systemically administered, has the poorest safety profile?
The following agents act by a mechanism involving fungal sterols (ergosterol) except:
Experts recommend taking which of the following antifungal agents with a fatty meal?
Viruses are difficult to treat because they cooperate with the host's cells.
Both parts of the statement are true
Which of the following is true of acyclovir?
It works by inhibiting replication of deoxyribonucleic acid (DNA)
Does not prevent the transmission of infection and does not prevent recurrence.
The oral form of acyclovir is indicated in the treatment of initial herpes genitalis and management of recurrent herpes genitalis infections in:
Both immunocompromised and nonimmunocompromised patients
Docosanol 10% has been shown to decrease healing time by about __________ in patients with recurrent orolabial herpes when started within 12 hours of the appearance of prodromal symptoms
One half day
Which of the following statements is true of zidovudine?
The toxicity of zidovudine
Which of the following agents is a nonnucleoside reverse transcriptase inhibitor used to treat HIV infection?
HIV-2 is only transmitted:
Via sexual intercourse
Which of the following groups of drugs used to treat HIV can interfere with the action of the HIV-infected cells?
Which of the following antiviral agents is used prophylactically for prevention of an influenza A viral infection or for treatment to reduce the symptoms of the infection?
The most common used of the interferons are for the treatment of:
Both b and c
(B. Hepatitis C AND C. Multiple sclerosis)
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