BB 1035 General Review
Terms in this set (11)
4 parts of cell signaling?
4 modes of signaling?
1. autocrine - affect cell that makes signal
2. juxtacrine - affect cells adjacent to cell that makes signal
3. paracrine - affect neraby cells
4. endocrine - circulates; long distance
3 types of genomics?
What is RB?
Tumor suppressor; mutation causes cancer
4 types of cell potency?
HATs vs HDACs
HATs - add positive charge; create euchromatin
HDACs - condense DNA; create heterochromatin
Euchromatin vs. heterochromatin
Euchromatin - Diffuse, stains lightly, contains DNA transcribed into mRNA
Heterochromatin - Condensed, stains darkly, contains genes not transcribed
Inducer that gives positional information; diffuses from one cell or group of cells to surrounding cells; sets up [ ] gradient
2 requirements to be considered a morphogen?
1. Directly affect targeted cells
2. Dif. [ ] of signal causes dif. effects
zone of polarizing activity
Formes gradient to determine axis of developing limb