Upgrade to remove ads
Only $2.99/month

Psoriasis

Terms in this set (46)

papulosquamous disease
skin dz characterized by primary lesions of scaly papulaes and plaques
Psoriasis
MC autoimmune disorder in USA
cutaneous hyper proliferative disorder
^ BMR of basal layer
Psoriasis
red, silvery, scaly papule w/ Auspitz's sign
Isomorphic Koebner's Phenomenon
psoriasis developing in the site of skin trauma
Drugs that cause psoriasis
lithium, BB, antimalarials, systemic steroids
Psoriasis vulgaris (plaque psoriasis)
elbows, knees, scalp, nails (extensor)
small/large plaques
sun can help
Gutatte Psoriasis
Acute eruption, with TEAR DROP shaped lesions
1-2 weeks after URI w. strep
Tx: abx
Pustular Psoriasis of palms and soles
tender pustular eruptions (painful)
pustules desquamate but do not rupture
common in smokers
tx resistant
pustular Psoriasis of digit
tender eroded and fissured surface (painful)
tx resistant
generalized pustular psoriasis
von Zumbush
tiny sterile pustules, coalescing into lakes of pus
feeble, toxic, inc WBC
tx: wet dressings, topical steroids
Erythrodermic Psoriasis
precipitating factor worsens state --> tachyphylaxis
tx: cool compress + MTX
red body wide, nail involvement tho
Inverse Psoriasis
red, smooth plaques that issue at base of body crease
intertriginous psoriasis (gluteal fold, groin, diaper)
Nail Psoriasis
nial pitting
onycholysis: lift of nail plate
sublingual hyperkeratosis
if nail matrix involved --> deformity
Psoriatic arthritis
RH(-)
tx: NSAIDs, gold, MTX, azathioprine
Asymmetric arthritis
60-70% Psoriatic arthritis
digit joints, sausage fingers
symmetric arthritis
15% psoriatic arthritis
resembles RA
RF (-)
distal interphalangeal joint dz
mid, chronic, a/w nail dz
destructive poly arthritis
osteolysis of small bones in hands/feet
gross deformity
joint subluxation
ankylosing spondylitis
sacroiliac arthritis
Pityriasis Rubra Pilaris (PRP)
thickened and yellow palms/soles, red skin all over, islands of sparing
starts w. red scaling plaque on face/upper body --> enlarges
thickened nails/ectropion
Tx: lubricants, Vit D3, retinoids
Childhood PRP
red to orange keratotic plaques confined to elbow and knees
seborrheic dermatitis
chronic papulosquamous dz
possible yeast overgrowth
cradle cap, tine amiantacea, blepharitis, classic
Tx: nizoral
cradle cap
infants w. greasy scale on scalp
tine amintacea
yeast
dense plaque on scalp of kids/teens
classic adult seborrheic dermatitis
white dry scale of scalp, eyebrows, ears, post auricular, bear, chest, axillae, groin
common w. parkinson's and AIDS pt
Pityriasis Rosea
single lesion (herald patch) on trunk (looks like ringworm) --> generalized 2* eruption
bright red oval papules/plauques w. fine collarette scale at periphery
xmas tree distribution
winter/summer outbreaks, benign, self limited, viral related
Lichen planus
inflammatory dermatosis
flat-topped, violaceous, shiny itchy papules and milky white papules in the mouth
5 P's
tx: corticosteroids
5 P's of Lichen planus
pruritic, planar, polyangular, purple, papules
Lichen planus
flat, purple papule w. white lines (Wickham's striae)
grouped linear, annular, or disseminated
wrists, lumbar, eyelid, shin, scalp, glans
mucous membranes 40-60%
LP actinic
sun-exposed areas
LP annular
trunk, external genitalia
LP atrophic
any area
LP erosioulcerative
soles, mouth
LP follicular
scalp
LP guttate
trunk
LP hypertropic
lower limbs, MC ankles
LP linear
zosteriform, scratched area
LP papular
localized
flexor surfaces
LP vesiculobuilous
lower limbs, mouth
Lichen straitus
U/L and linear
red, flat, scaly papules that extend limb length
lichen sclerosis et atrophicus (LSA)
mucocutaneous disorder
white angular, well defines, indurates papules/plaques
tx: corticosteroids
LSA appearance
whitish, sharp demarcated, macule and forming plaques w. Keratin plugs
SCC can develop at genitalia
kraurosis vulvae
female anogenital vulvar plaques w/ keyhole or hour shaped arrangement; vulva may atrophy; fusion of labia minora & majora
a/w LSA
balanitis xerotica obliterans
prepuce becomes sclerotic and cannot be retracted leading to phimosis
a/w LSA
Pityriasis Lichenoides et Varioliformis Acuta (PLEVA)
papulosqaumous: red/brown papulonecrotic clusters
trunk + extremities
benign self limited
Pityriasis Lichenoides Chronica (PLC)
brownish papules w/ scale that may persist for years
tx: erythromycin
THIS SET IS OFTEN IN FOLDERS WITH...