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Anticholinergic drugs such as atropine or glycopyrrolate (Robinul)
Inhibit gastric acid secretion and depress gastrointestinal (GI) motility (Lehne, 2010) (Although useful in treating hyperactive bowel disorders, anticholinergics cause constipation.)
Produce diarrhea by disrupting the normal bacterial flora in the GI tract (An increase in the use of fluoroquinolones in recent years has provided a selective advantage for the epidemic of Clostridium difficile)
Nonsteroidal antiinflammatory drugs
Cause GI irritation that increases the incidence of bleeding with serious consequences to older adults; rectal bleeding is often observed with GI irritation
Prostaglandin inhibitor; interferes with the formation and production of protective mucus and causes GI bleeding
Histamine2 (H2) antagonists
Suppress the secretion of hydrochloric acid and interfere with the digestion of some foods
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