GI Medications

Neutralize or reduce the acidity of stomach contents.
Histmaine (H2) receptor blockers
Decrease acid secretions by blocking histamine receptors.
Proton pump inhibitors
Antisecretory agents that inhibit secretion of gastrin by the parietal cells of the stomach.
Mucosal healing agent
Heals ulcers without antisecretory properties. Sucralfate is a cytoprotective drug. It accelerates wound healing, presumably because of the formation of an ulcer-adherent complex that covers the ulcer and protects it from evasion by pepsin, acid, and bile salts.
Antisecretory and cytoprotective agent
Inhibits gastric acid secretion and protects gastric mucosa. Cytotec is the only drug approved in the U.S. for the prevention of gastric ulcers induced by NSAIDs and aspirin.
Antibiotic therapy
Eradicates H. pylori (Flagyl & Biaxin)
Lactulose (Chronulac)
Decreases absorption of ammonia from the gut.
Inhibits protein synthesis in bacteria therefor reducing ammonia producing bacteria in the gut.
Meperidine (Demrol)
Used in biliary pain because Morphine may cause spasm of the sphincter of Oddi.
Spironolactone (Aldactone)
Results in the excretion of Na, water, from ascites.
Vasopressin (Pitressin)
A potent vasoconstrictor
Pancrelipase (Pancrease)
Increase digestion of fats, CHO, and proteins in the digestive tract.
Propanthelilne (Pro-Banthine)
A antispasmotic agent that slows motility
Kaolin and pectrin (Kaopectate)
Antidiarrheal that may interfere with absorption of nutrients and other drugs.
Bisacodyl (Dulcolax)
Laxative that is a stimulant that may cause rectal irritation if used in suppository form.
CimetidINE (Tagamet)
H2 receptor blocking agent that interacts with warfarin.
OmeprazOLE (Prilosec)
Medication that inhibits enzymes that produce gastric acid and should not be crushed or chewed.
Sucralfate (Carafate)
Works as a mucosal barrier fortifier and should be taken on an empty stomach.
Diphenoxylate/atropine (Lomotil)
Antidiarrheal agents that may cause central nervous system depression.
Anti-infective agent used in the treatment of clients with Chron's disease or ulcerative colitis.
Aluminum-Magnesium (Maalox)
Used to neutralize gastric secretions.
Promethazine (Phenergan)
Antiemetic that causes central nervous system depression.
Antifungal you instruct client to swish, hold in mouth, then swallow.
Psyllium (Metamucil)
Bulk-forming laxative that often required reconstruction with water.
Bismuth subsalicylate (Pepto-Bismol)
Antidiarrheal that should not be given to clients who are allergic to aspirin.
Metoclopramide (Reglan)
Medication used to stimulate motility of the GI tract.
LansoprazOLE (Prevacid)
Proton pump inhibitor that the client should be assessed for epigastric or abdominal pain and blood in stools.
RanitidINE (Zantac)
Works to inhibit and reduce gastric acid secretions by blocking H2 receptors and should not be given within 1 hour of antacids.