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BIO 316 Quiz 4
Terms in this set (46)
Human have __________ copies of each chromosome.
Because of #1, we are considered to be ____________.
Homologous chromosomes means that the pair has the same ________ in the same order.
True or false: a gene and an allele are the same thing?
An allele is a _____________ of a gene.
Gene is to eyes as allele is to ____________ ____________.
In diploids, like us, each gene has _________ copies.
Each person gets one chromosome from __________ and one chromosome from _________.
If a trait requires two alleles to be expressed, it's said to be __________.
If a trait requires one allele to be expressed, it's said to be _____________.
The number of individuals with certain alleles in the population is said to be the ___________.
If the two alleles on the two homologous chromosomes are the same, they are ________________.
If the two alleles on the two homologous chromosomes are the different, they are ________________.
The study of ________________ has given us much of our current understanding of the relationship between inherited mutations and the development of cancer.
The two-hit model is the __________ form of RB and is non-_____________.
The presence or absence of an oncogene is dangerous?
The presence of absence of the RB gene is dangerous?
Gene that stop cell proliferation are call __________ _____________ ___________.
tumor suppressor genes
The acronym for an inherited risk factor of colon cancer is the gene _______.
The gene that is mutated in #6 is called _______.
The presence or absence of the WNT gene is dangerous?
Li-Fraumeni Syndrome is caused by inherited defects in the _________ gene.
True or false: Li-Fraumeni Syndrome can cause many kinds of cancer at an early age.
Tumor-suppressor genes are also called _________ ______________.
Genes involved in DNA maintenance are called __________ _____________.
Loss of a caretaker does or does not directly influence cell proliferation?
Xeroderma Pigmentosum is caused by inheriting _________ from both parents.
Xeroderma Pigmentosum is a dominant or recessive trait?
Will you know if you have a mutation in a recessive gene?
One mechanism for repairing pyrimidine dimers (thymine dimers) is the ___________ _________ pathway.
The reason xeroderma pigmentosa cannot repair ____________ ___________, they exhibit skin cancer rates ___________-fold higher than average.
pyrimidine dimers, 2000
Before an oncogene is mutated it's called a ___________-______________.
Many of these genes came from ______________.
A loss-of-function mutation in the DNA leads to proteins that are activated or inactivated.
A gain-of-function mutation in the DNA leads to proteins that are activated or inactivated.
It takes one __________-___-_________ mutation in a proto-oncogene to become an oncogene.
It takes two __________-___-_________ mutations in a tumor suppressor gene to become an oncogene.
Normal genes that can be converted to an oncogene are called ___________ -oncogenes
True or false: A virus can infect a person with oncogenes
To distinguish innate and foreign oncogenes, they are named ___________ oncogenes if they come from a virus, and ___________ oncogenes if they are innate
What are the five categories of mutations in genes?
Category of mutation where one base is exchanged for another?
Category of mutation where a gene is duplicated?
Category of mutation where an entire chromosome is rearranged in the genome?
Category of mutation where a segment of DNA is moved?
Category of mutation where a segment of DNA is inserted into the genome?
Recommended textbook explanations
Fundamentals of Biochemistry
Charlotte W. Pratt, Donald Voet, Judith G. Voet
Campbell Biology (AP Edition)
Cain, Jackson, Minorsky, Reece, Urry, Wasserman
Biocalculus: Calculus, Probability, and Statistics for the Life Sciences
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