DNA replication, transcription and translation
Terms in this set (9)
Explain DNA replication in terms of unwinding the double helix and separation of the strands by helicase, followed by formation of the new complementary strands by DNA polymerase.
DNA replication is a semi-conservative process because the new DNA helix is formed both from old strand and new strand. DNA helicase first unwinds the double helix. There are free nucleotides present around the replication fork and DNA polymerase enzyme connects them to the old (template) strand using the complementary base pairing (A+T, C+G). Hydrogen bonds are again created between the complementary bases and new DNA strands rewind to form a double helix. The replication process has produced a new DNA molecule which is identical to the initial one.
Explain the significance of complementary base pairing in the conservation of the base sequence of DNA.
Complementary base pairing is very important in the conservation of the base sequence of DNA. This is because adenine always pairs up with thymine and guanine always pairs up with cytosine. As DNA replication is semi-conservative (one old strand an d one new strand make up the new DNA molecules), this complementary base pairing allows the two DNA molecules to be identical to each other as they have the same base sequence. The new strands formed are complementary to their template strands but also identical to the other template. Therefore, complementary base pairing has a big role in the conservation of the base sequence of DNA.
Compare the structure of DNA and RNA
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types of RNA
central dogma of biology
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