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early disease, mild focal weakness, asymmetrical distribution
symptoms of hand cramping and fasciculation (LMN signs)
moderate weakness in groups of muscles
some wasting (atrophy) of muscles
modified independence with assistive devices
severe weakness of specific muscles, increasing fatigue
mild to moderate functional limitations, ambulatory
severe weakness and wasting (atrophy) of LEs
mild weakness of UEs, moderate assistance
assistive devices required, wheelchair user
progressive weakness with deterioration of mobility and endurance, increased fatigue
moderate to severe weakness of whole limbs and trunk
spasticity; hyperreflexia (UMN signs); loss of head control
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