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Terms in this set (172)

Type 1 Diabetes Mellitus is an autoimmune disease in which the body does not produce insulin. Although it is an autoimmune disease, genetics and environmental factors play a role in the development of this disease. In T1DM, the body's immune response leads to complete pancreatic Beta cell destruction. A person with T1DM will be insulin deficient and, therefore, require insulin therapy for the rest of his/her life. Symptoms of T1DM include hyperglycemia, polyuria, polydipsia, dehydration, electrolyte imbalance, polyphagia, sudden weight loss, fatigue, and ketoacidosis.
Type 2 Diabetes Mellitus is both preventable and reversible. It is a condition in which the body is resistant to insulin and the body cannot make enough insulin to keep up with rising blood glucose levels. T2DM is caused by genetics and environmental factors, such as excess weight and physical inactivity. Symptoms of T2DM may not be present but can include hyperglycemia, polyuria, polydipsia, dehydration, electrolyte imbalance, polyphagia, sudden weight loss, and fatigue. T2DM may go undiagnosed for years so complications may develop, such as kidney disease. Treatment includes lifestyle changes and possibly medication and insulin therapy depending on the severity.
LADA is Latent Autoimmune Diabetes. LADA is similar to T1DM except for it progresses slowly and can be mistaken for Type 2 Diabetes Mellitus. General criteria for diagnosing diabetes mellitus is an A1c of 6.5%, fasting plasma glucose of 126 mg/dL, the symptoms of diabetes plus random plasma glucose concentration of 200 mg/dL, or 2-hour post-prandial glucose of 200 mg/dL during an oral glucose tolerance test.