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Antimicrobial Drug Questions
Terms in this set (25)
There are a number of antimicrobial drugs available that cover a broad spectrum of microbes. Why is it necessary for companies to continue their development of new antibiotics?
Because of resistance
Which group of antibiotics are more likely to promote resistance?
Why do we see more antibiotic resistance in a hospital?
We use more of them → the microbes are exposed to more antibiotics → the risk of resistance increases
You are caring for a newly admitted client with an infected diabetic foot ulcer. The admission orders include:
Send culture and sensitivity
IV -- 0.9% NS at 75 ml/hr
Cefazolin 1gm IV Q8hr
- Assessment - Swelling, temperature, WBC count, allergies, current meds, pregnancy, age, know what drug does and how to give it!!!!
- Planning - Send culture and sensitivity, host factors such as renal problems
- Intervention - IV -- 0.9% NS at 75 ml/hr, Cefazolin 1gm IV Q8hr
- Evaluation - See if symptoms have improved, possibly take another culture (would want to see a negative culture)
Is penicillin G a narrow or broad spectrum antibiotic?
Which penicillin is considered broad spectrum? (Nafcillin, Ampicillin)
A client has a penicillin allergy, is there any risk in giving her amoxicillin?
Yes, bc if you're allergic to one penicillin you're allergic to all of them
What other antibiotics might be given for patients with a penicillin allergy?
Erythromycin, Clindamycin, Vancomycin
What are the symptoms of an anaphylactic penicillin reaction? What nursing actions would implement for a patient with a penicillin anaphylaxis?
Bronchoconstriction, massive vasodilation, laryngeal edema (these are the 3 classic symptoms of anaphylaxis)
Nursing actions: stop the med infusion, give epinephrine
Why can't penicillins and aminoglycosides be given in the same IV solution?
Penicillins will inactivate the aminoglycosides
Which form of pen G would you avoid in a client who is at risk for hyperkalemia?
Potassium penicillin G
How many generations of cephalosporins are there? What generation/s of cephalosporins cross the CSF?
3rd, 4th, and 5th
Are the cephalosporins bacteriostatic or bactericidal?
Mary has a severe penicillin allergy. Can I safely administer a cephalosporin?
Possibly, but you would want to consider the type of reaction that she has had, if anaphylaxis it is def. a no, if any questions just call the provider.
What are the two most common side effects?
Thrombophlebitis and allergy
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