NAME

Question types


Start with


Question limit

of 30 available terms

Advertisement Upgrade to remove ads
Print test

5 Written questions

5 Matching questions

  1. DMARD MOA
  2. Chlorambucil
  3. Dexamethasone
  4. Calcineurin Inhibitors MOA
  5. DMARD clinical Uses
  1. a DNA-Alkylating Agent
    Clinical Uses: prevention/reversal and reversal of graft rejection
    Treatment of auto-immune disease
    SLE
    Myasthenia Gravis
  2. b Corticosteroid
    Immunosuppressant
    Long-action
    MOA: DMARD
    Tox: DMARD
  3. c prevention of acute allograft rejection
    Treatment of all inflammatory conditions
    Short-term anti-inflammatory
  4. d prevent Ca2+ binding to calcineurin
    black signal transduction pathway
    Prevents IL-2 produciton
    Prevents T-cell proliferation
    B cell phagocyte function spared
  5. e inhibits transcription of inflammatory mediators
    Increase some anti-inflammatory regulator genes
    Decrease production of cytokines
    Reduced expression of adhesion molecules =decreased leukocyte adhesion

5 Multiple choice questions

  1. Cytotoxic Drug
    MOA: Folic acid antagoinst
    Clinical Uses: Rheumatoid arthritis Gold standard drug
  2. Leukemia/lymphoma Therapy
    MOA: CD20 binding, Blocks Ca2+ channel on B-cell
    Clinical Uses: CLL, B-cell lymphoma
  3. Lymphocyte Trafficking Inhibitors
    MOA:alpha-4 integrin blocks vascular adhesion molecuels prevents T lymphocyte entry into brain or gut
    Clinical Uses: Relapsing MS, Crohns Disease
    Adverse Effects: Risk ofr multi focal leukoencephalopathy
  4. Cancer Treatment
    MOA: HER2/neu, Growth Factor receptor
    Clical Uses: Breast Cancer
  5. DNA-Alkylating Agent
    Clinical Uses: prevention/reversal and reversal of graft rejection
    Treatment of auto-immune disease
    SLE
    Myasthenia Gravis

5 True/False questions

  1. OmalizumabImmunosupressant
    MOA: IgE antagonist
    Clinical Uses: Asthma

          

  2. Cytokines Effected by DMARDSAspirin
    Ibuprophen
    Naproxene
    Celecoxib

          

  3. DaclizumabLymphocyte Trafficking Inhibitors
    MOA:alpha-4 integrin blocks vascular adhesion molecuels prevents T lymphocyte entry into brain or gut
    Clinical Uses: Relapsing MS, Crohns Disease
    Adverse Effects: Risk ofr multi focal leukoencephalopathy

          

  4. AnkinraIL-1 cytokine antagonist
    Soluable Ligand Receptor Drugs
    MOA: sIL1 receptor antagonist
    Clinical Uses: RA

          

  5. SirolimusCalcineurin Inhibitor
    MOA: binds FK protein inhibits IL-2 Secretion and other cytokines
    Clinical Use: Prevention/Rejection of organ transplantation
    Toxcities: Nephrotoxic, Diabetes, peripheral neuropathy