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Physiology I review
Terms in this set (23)
Name the two ANS transmitters?
Acetylcholine and Norepinepherine
What are the name for the fibers that release acetylcholine? What preganglionic fibers release acetylcholine?
1. Cholinergic Fibers
2. All ANS preganglionic fibers release acetylcholine
Acetylcholine are mostly released by what part of the ANS? What type of transmitters are these?
1. Acetylcholine is mostly released by parasympathetic postganglionic fibers.
2. Acetylcholine are parasympathetic transmitters
What are the name for the fibers that release norepinephrine? What part of the ANS release norepinephrine?
1. Fibers that release norepinephrine are called adrenergic fibers
2. Norepinephrine is mainly released by sympathetic postganglionic fibers
Note: Postganglionic fibers to sweat glands and piloerector muscles release acetylcholine. Postganglionic fibers to some blood vessels release acetylcholine
What type of transmitter is norepinephrine considered to be?
A sympathetic transmitter
Cholinergic have 2 types of receptors what are they? What are the two activated by?
Muscarinic (activated by muscarine and acetylcholine)
Nicotinic (activated by nicotine and acetylcholine )
Muscarinic receptors are receptors of what ganglionic fibers? These are coupled by what?
1. Receptors on effector organs that are inner aged by parasympathetic fibers.
2. Coupled by G-proteins
On what 3 locations are nicotinic receptors found? What type of transport are these receptors usual affiliated with?
1. Receptors on postganglionic fibers of all autonomic fibers
On neuromuscular junction of skeletal muscle
Found widely on neurons in brain
2. Usually affiliated with ion channels
Adrenergic have 5 types of receptors, what are they? What type of responses are these receptors responsible for? What does the responses depend on?
1. Alpha 1 and Alpha 2
Beta 1, Beta 2, Beta 3
2. Excitatory or inhibitory
3. Depend. On the effector organ
How much norepinephrine and epinephrine are secreted by the adrenal medulla?
Norepinephrine have a main affect on what receptors and a small affect on what other receptors?
Main affect on alpha receptors
Small affect on beta receptors
Epinephrine excites what type of receptor?
Both alpha and beta
What are the three basic principles of circulation?
1.Control of blood flow is dependent on metabolic needs of tissue.
Constrict/ diamanté of metarteriales and Precap sphincters, Works when pressure across capillaries does not change.
2.Venous return is the sum of all BF leaving all tissues and cardiac output is driven by venous return.
Starlings law- changes in preload, changes in intrinsic contractility
3. Control of BP is independent of BF through local tissue and control of CO
Changes and control of blood pressure is a response to what?
1. Response to moment to moment changes
2. Response to changes in pressure over entire range
3. Response specifically to pressure dropping below normal MAP
When dealing with moment to moment responses in BP, what mechanisms take affect?
Baroreceptors- Able to respond to either an increase or a decrease increase in pressure relative to normal MAP
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