Upgrade to remove ads
Chapter 17 key terms
Terms in this set (60)
most dramatic stage of cell cycle, (nuclear division) corresponding to the separation of daughter chromosomes
period of cell cycle between mitoses that include G1, S, and G2 phases
division of cell following mitosis or meiosis.
mitotic phase; the phase of the cell cycle that includes mitosis and cytokinesis
(gap 1) that corresponds between mitosis and initiation of DNA replication
(synthesis) Phase of the cell cycle during which DNA replication occurs.
Gap 2 where cell growth continues and proteins are synthesized in preparation for mitosis.
Instrument that counts cells in a suspension by measuring the scattering of light by individual cells as they pass by a laser
fluorescence-activated cell sorter
sorts individual cells on the basis of their fluorescence intensity
regulatory point in the yeast cell cycle that occurs late in G1. After this point a cell is committed to entering S and undergoing one cell division cycle.
A regulatory point in animal cell cycles that occurs late in G1. After this point, a cell is committed to entering S and undergoing one cell division cycle.
cell cycle checkpoints
"checkpoints" where the cell cycle either stops or continues; internal signaling proteins called cyclins regulate whether the cell proceeds to the next stage
DNA damage checkpoints
ensure that damaged DNA is not replicated and passed on to daughter cells
spindle assembly checkpoint
checkpoint that monitors alignment of chromosomes on the metaphase spindle
Maturation Promoting Factor (MPF)
A complex of Cdk1 and cyclin B that promotes entry into the M phase of either mitosis or meiosis
A serine / threonine kinase that is a key regulator of mitosis in eukaryotic cells
Member of a family of proteins that regulate the activity of Cdk's and control progression through the cell cycle
Anaphase promoting complex/cyclosome (APC/C)
A ubiquitin ligase that triggers progression from metaphase to anaphase by signaling the degradation of cyclin B and cohesins.
G1 cyclins or Cln's
A yeast cyclin (also called G1 cyclin) that controls passage through START
cyclin-dependent kinases drive progression through different stages of the cell cycle
Cdk inhibitors or CKls
Member of a family of proteins that bind Cdk's and inhibit their activity
tumor suppressor gene that acts as breaks to slow down cell cycle
tumor suppressor gene
A gene whose protein products inhibit cell division, thereby preventing uncontrolled cell growth (cancer).
transcription factor which regulates expression of several genes involved in cell cycle progression (can bind with or without Rb)
A protein kinase (Chk1 or Chk2) that brings about cell cycle arrest in response to damaged DNA
A protein kinase related to ATM that leads to cell cycle arrest in response to DNA damage single-stranded or unreplicated
a protein kinase that recognizes damaged DNA double-strand break and leads to cell cycle arrest
A transcription factor (encoded by the p53 tumor suppressor gene) that arrests the cell cycle in G1 in response to damaged DNA and is required for apoptosis induced by a variety of stimuli
The beginning phase of mitosis, marked by the appearance of condensed chromosomes and the development of the mitotic spindle
The phase of mitosis during which the chromosomes are aligned on a metaphase plate in the center of the cell
The phase of mitosis during which sister chromatids separate and move to opposite poles of the spindle
The final phase of mitosis, during which the nuclei re-form and chromosomes decondense
A specialized chromosomal region that connects sister chromatids and attaches them to the mitotic spindle
A specialized structure consisting of proteins attached to a centromere that mediates the attachment and movement of chromosomes along the mitotic spindle
The microtubule-organizing center in animal cells
An array of microtubules extending from the spindle poles that is responsible for separating daughter chromosomes during mitosis.
A transition period between prophase and metaphase during which the microtubules of the mitotic spindle attach to the kinetochores and the chromosomes shuffle until they align in the center of the cell
A protein kinase family involved in mitotic spindle formation, kinetochore function, and cytokinesis
A protein kinase involved in mitotic spindle formation, kinetochore function, and cytokinesis
A protein complex that drives metaphase chromosome condensation
A protein that maintains the connection between sister chromatids
mitotic checkpoint complex (MCC)
checkpoint complex (MCC)
A complex of proteins that is formed at unattached kinetochores and inhibits progression to anaphase until all chromosomes are aligned on the metaphase spindle
The division of diploid cells to haploid progeny, consisting of two sequential rounds of nuclear and cellular division
A structure of actin and myosin II that forms beneath the plasma membrane during mitosis and mediates cytokinesis
initial stage of the extended prophase of meiosis I during which homologous chromosomes pair before condensation
stage of meiosis I during which homologous chromosomes become closely associated
stage of meiosis I during which recombination takes place between homologous chromosomes
stage of meiosis I during which homologous chromosomes separate along their length but remain associated at chiasmata
Final stage of prophase of meiosis I during which the chromosomes fully condense and the cell progressed to metaphase
the pairing of homologous chromosomes during meiosis
A zipperlike protein structure that forms along the length of paired homologous chromosomes during meiosis.
The X-shaped, microscopically visible region representing homologous chromatids that have exchanged genetic material through crossing over during meiosis.
A small cell with extremely little cytoplasm that results from the unequal cytoplasmic divsion of the primary (produces the first polar body) and the secondary (produces the second polary body) oocytes during meiosis (oogenesis). The polar bodies degenerate.
cytostatic factor CSF
cytoplasmic factor that arrests oocyte meiosis at metaphase II
protein kinase that is required for progression from meiosis I to II and for maintenance of metaphase II arrest in vertebrate oocytes
The union of a sperm and an egg
A fertilized egg
One of the two haploid nuclei in a newly fertilized egg
-Cyclin D -- inhibits cdk4 and cdk6
which restriction point in G1
bind to cyclins and inhibit Cdk2 with cyclin A or cyclin E which inhibits entry into S phase
YOU MIGHT ALSO LIKE...
Cell Bio test 4
Chapter 8: Cell Reproduction Part 1/2
Biology Ch. 10
OTHER SETS BY THIS CREATOR
Molecular chapter 17 Cell Cycle
Chapter 16 key terms
Chapter 12: Mitochondria, Chloroplasts, and Peroxi…