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NUS 221 - Pharmocology - Key Terms S2
Pharmacology (Internet) SP14 Kalinowski - NUS 221 540 - Spring 2014
Terms in this set (25)
How the unchanged drug moves from the administration site to the site of measurement
A drug that binds to and stimulates the activity of one or more receptors in the body
A drug that binds to and inhibits the activity of one or more receptors in the body. Antagonists are also called inhibitors.
Blood vessels (capillaries) that selectively let certain substances enter the brain tissue and keep other substances out. It is formed by a continuous endothelium of capillary walls and feet of astrocytes. It helps maintain a stable environment for the brain and seperates neurons from some blood borne substances
A vector quantity, commonly denoted by the vector s, which reflects an object's change in spatial position. The displacement vector points from the object's starting position to the object's current position in space. If an object is moved from point A to point B in space along path AB, the magnitude of the object's displacement is the separation of points A and B. Note that the path an object takes to get from point A to point B does not figure when deining displacement.
2nd stage of the Pharmacokinetic process which involves the transport of the medication within the body once it enters the circulatory system
duration of action
The time span beginning at the onset of action up to the termination of action in which the drug produces the therapeutic activity.
4th stage of the Pharmacokinetic process where the effect of medication in the body continues until it is biotransformed and eliminated
the name established when the drug is first manufactured ,this name is protected for use only by the original manufacturer for period of 17 years.after that time the name of the drug becomes public property and can be used by manufacturer..
hepatic enzyme induction
decrease in concentrations of affected drug
hepatic enzyme inhibition
increase in concentrations of affected drug (interaction goes away faster), Decreases hepatic enzymes. Drug stays in system longer. dangerous with SSRI's (increase dosage)
Allergic immune response to a substance causing a range of symptoms from mild inflammation to anaphylactic shock and death
Anything that impedes the communication of a message
Chemical processes occurring in cells; including catabolism (breaking down process) and anabolism (building up process)
onset of action
The time required for the drug to elicit a therapeutic response.
peak and trough levels
highest and lowest plasma concentration of a drug at a specific time; timing of peak depends upon route of admin.; indicate the rate of elimination
Action/Rate at which the drug action begins and duration. Includes ADME (absorption, distribution, metabolism, elimination).
the ability of certain drugs to bind to plasma protein. This is important in determining amount of available drug at the site of action, toxicity and other relevant physiological effects
The amount of time it takes for half of the blood concentration to be eliminated from the body; this determines when the next dose is given
Any enhancing drug interaction. Synergistic drugs, when taken together, have a great effects than the effects of taking either drugs alone.
Agents, such as chemicals and viruses, that can reach the embryo or fetus during prenatal development and cause harm
Defined by either a need for markedly increased amounts of the substance to achieve intoxication or the desired effect or a significantly diminished effect with continued use of the same amount of the substance.
trade (brand) name
AKA: Proprietary (ownership); Assigned by the pharmaceutical company marketing the drug; Written as a proper noun, with the first letter capitalized, followed by the ® symbol, & in parentheses; More than one trade name exists for each generic name; Intentionally shorter and easy to remember for consumers
THIS SET IS OFTEN IN FOLDERS WITH...
NUS 221 - Pharmocology - Key Terms S3
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