Acquired immunodeficiency syndrome (AIDS)
Depression or suppression of the immune system after exposure to the human immunodeficiency virus (HIV); marked by opportunistic infections, secondary neoplasms, and neurologic problems.
Protein produced in the bloodstream by lymphocytes in response to a specific antigen, such as a bacterium or toxin. Antibodies destroy or weaken antigens.
Intense allergic reaction (such as asthma) influenced by hereditary tendency or predisposition.
Chronic disabling disease caused by the abnormal production of antibodies to normal body tissues; multiple sclerosis, lupus erythematosus are examples.
A lymphocyte that originates in bone marrow and transforms into a plasma cell to secrete antibodies.
Type of immune response that involves T cell lymphocytes. These lymphocytes act directly on antigens to destroy them.
A type of macrophage that captures antigens and presents them to T cells for destruction.
Helper T cell
Lymphocyte that aids a B cell lymphocyte in recognizing antigens and stimulating antibody production.
Type of immune response in which a B cell lymphocyte transforms into a plasma cell and secretes antibodies.
Abnormal condition characterized by an exaggerated response of the immune system to an antigen.
Syndrome of spleen enlargement (splenomegaly) and destruction of red blood cells (hemolysis).
The body's capability to resist foreign organisms and toxins that can damage tissue and organs.
Proteins (cytokines) that stimulate the immune system including B & T cell lymphocytes.
Abnormal collection of fluid in tissue spaces caused by obstruction of lymph vessels and backflow of lymph.
White blood cells that develop primarily in lymph nodes and the spleen and fight against foreign organisms.
Organs containing and derived from lymphatic tissue; spleen, thymus gland and lymph nodes.
Large phagocyte found in lymphatic tissues and connective tissues; derived from a monocyte.
Person's own genetic ability to fight off disease. It includes phagocytes and lymphocytes such as natural killer cells.
Natural killer cell
Lymphocyte that recognizes and destroys foreign cells by releasing proteins called cytokines.
Malignant tumor of cells (lymphocytes and large macrophages called histocytes) found in lymph nodes and spleen
Infectious diseases associated with AIDS; toxoplasmosis, tuberculosis, herpes simplex, and Pneumocystosis carinii pneumonia (PCP).
Protease inhibitor (PI)
Drug used to treat AIDS by blocking production of protease, an enzyme that helps HIV to reproduce.
Virus that makes copies of itself using the host cell's DNA, a process that is the reverse of the normal replication mechanism in cells. HIV is a retrovirus.
Reverse transcriptase inhibitor
Drug used to treat AIDS by blocking an enzyme (reverse transcriptor), needed to make copies of HIV.
Right lymphatic duct
Receives lymph from the right side of the body and empties lymph into a vein in the neck.
Organ adjacent to the stomach (in the LUQ) that produces, stores, and eliminates blood cells.
Lymphocyte originating in the thymus gland and destroys antigens by direct action or production of cytokines such as interferons and interleukins.
Lymphoid organ in the mediastinum that produces T cell lymphocytes and aids in the immune response.
Introduction of a vaccine (containing dead or weakened antigen) to produce immunity. It is a type of acquired immunity.
Weight loss and decrease in muscle strength, appetite, and mental activity that occurs with AIDS.