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BC Nursing: Pharm S1 - Lipid Lowering Agents

STUDY
PLAY
Atorvastatin (Lipitor)

Simvastatin (Zocor)

Therapeutic Class?

Pharmacologic Class?
T: Lipid-Lowering Agents

P: HMG-CoA Reductase Inhibitors "Statins"
Atorvastatin (Lipitor)

Simvastatin (Zocor)

Main Action
Prevents synthesis of cholesterol by the liver.
Atorvastatin (Lipitor)

Simvastatin (Zocor)

Indication
Elevated LDLs.
Atorvastatin (Lipitor)

Simvastatin (Zocor)

Side Effect/Adverse Reaction
Liver toxicity, Gl disturbances, rhabdomyolysis.
Atorvastatin (Lipitor)

Simvastatin (Zocor)

Assessments/Implementation/Evaluation
Monitor for diarrhea and constipation, muscle pain and weakness; some may need to be given with evening meal to decrease Gl upset.
Atorvastatin (Lipitor)

Simvastatin (Zocor)

Patient Teaching
Do not eat grapefruit.

Report muscle aches and dark colored urine.

Have periodic liver function tests.

Do not take if pregnant or breast feeding.