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Pharm ATI - Chapter 11 (Mental Health for Kids)

Terms in this set (29)

CNS stimulants - type and length
Methylphenidate (all 3), dexmethylphenidate (short or long), dextroamphetamine (short and long), amphetamine mixture (short and long), lisdexamfetamine dimesylate (long only)
CNS stimulant - Action
raise NE and DA levels in CNS
CNS stimulant - Uses
ADHD, conduct, narcolepsy, obesity
CNS stimulant - side effects
CNS stimulation, decreased appetite, weight loss, growth suppression, CV effects, development of psychotic manifestations, physical tolerance/withdrawal reaction, hypersensitivity (transdermal), toxicity
CNS stimulant - Interactions
MAOIs (Hypertensive crisis), concurrent use of caffeine (increases stimulation), inhibited metabolism of phenytoin, warfarin, and phenobarbitol, increased CNS stimulation with OTC cold and decongestant meds
NSRI - names
Atomoxetine, buproprion
NSRI - Action
block NE reuptake
NSRI - Uses
ADHD, dperession
NSRI - side effects
appetite suppression/weight loss/growth suppression, GI effects, SI, hepatotoxicity, seizure activity
NSRI Interactions
MAOIs (hypertensive crisis), paroxetine/fluoxetine/quinidine
TCAS - Names
desipramine, imipramine, clomipramine
TCAS - Action
block NE and serotonin reuptake
TCA uses (children)
depression, Autism spectrum disorder, ADHD, panic/social phobia/separation anxiety, OCD
TCA - side effects
orthostatic hypotension, ACh effects, weight gain, sedation, toxicity, decreased seizure threshold, excessive sweating
TCA - indications
MAOIs, antihistamines, decreased effectiveness of epi, NE, ephedrine, and amphetamine, alcohol/benzos/opioids/antihistamines cause CNS depression
Medication Effectiveness
Depression: verbalized better mood, improved sleeping/eating, increased peer interactions
Autism: decreased anger, agitation, and compulsive behavior
ADHD: less hyperactivity, greater ability to pay attention
Alpha2-adrenergic agonists - Names
Guanfacine, clonidine
Alpha2 agonists - uses
ADHD
Alpha 2 agonist - side effects
CNS effects, hypotension, bradycardia, weight gain
Alpha 2 agonist - Interactions
CNS depressants, antihypertensives, foods with high-fat content
Atypical Antipsychotics - names
risperidone, olanzapine, quetiapine, aripiprazole
Atypical - action
blocking serotonin and dopamine (aripiprazole is partial agonist)
Atypical - uses
Autism spectrum disorder, conduct disorder, PTSD, psychotic symptom relief, intermittent explosive disorder
Atypical - side effects
Metabolic syndrome, weight gain, hypercholesterolemia, orthostatic hypotension, anticholinergic effects, agitation, dizziness, sedation, sleep disruption, mild extrapyramidal adverse effects, agranulocytosis, neutropenia, hyperprolactinemia
Atypical interactions
alcohol, opioids, antihistamines, levodopa, TCAs, amiodarone, clarithromycin, barbiturates, fluconazole
SSRI - names
fluoxetine, sertraline
SSRI - uses
Autism spectrum disorder, OCD, MDD, intermittent explosive disorder, bulimia nervosa
SSRI - side effects
serotonin syndrome, weight gain, withdrawal syndrome, SI, EPS, dizziness, fatigue, insomnia, agitation, sexual dysfunction, dysrhythmias
SSRI interactions
MAOIs, SNRIs, buspirone, phenothiazines, elevation of TCAs and Lithium, antiplatelet/anticoags
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