what does it stand for?
what does it detect?
what probes are often used?
Good tool to identify what genetic mutations?
when will FISH not descriminate?
what diseases can FISH be used to detect?
Florescent In Situ Hybridization
used to detect large deletions
bacterial artificial chromosome (BAC) probes often used
If the probe is larger than the deletion, it will not descriminate
Good to identify multiple congenital anomalies, translocation, and trisomies
Used to detect
Williams syndrome, DiGeorge syndrome, Prader Willi, and Anglemann