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Important Infections - Antibiotics with dosing, Pain management

Terms in this set (24)

What are some empiric antibiotic choices for General gram + infections?
penicillin
Cephalosporins
Clinda
Tetracyclines
Carbapenems
Bactrim
Vanco
What are some general empiric antibiotics to cover MRSA?
Bactrim, Clinda, Doxy, Dapto, Rifampin, Synercid, Vanco, Zyvox
What are some general empiric antibiotics to give for Gram negative infections like E. Coli and Proteus
Cephalosporins
Penicillins
Ciprofloxacin
What is the drug of choice and dosage for E.coli infections?
Cephalexin (Keflex)
500 mg po q8
What does second generation cephalosporins cover?
HEN PECK
What is the dosage for Augmentin?
875 mg po q12hrs
what are some antibiotics to treat diabetic foot infections?
Augmentin 875 mg po q12
Cefazolin + Metronidazole (500 mg po q6)
biomarker that exhibits greater specificity than other proinflammatory markers (such as cytokines) in identifying patients with sepsis and can be used in the diagnosis of bacterial infections
procalcitonin
what is the procalcitonin levels that will correlate with increased bacterial load and positive blood cultures
>0.25
what is lactate level a marker for?
cellular hypoxia
What are some indications for the use of Augmentin?
Enterococcus infection
Diabetic foot infection
What is a good PO drug of choice for a patient with a MRSA infection?
Doxycycline
What antibiotic will you rarely use for lower extremity infections because of the polymicrobial nature of these infections
penicillin by itself
amoxicillin
ampicillin
What type of infectious agent causes blanching cellulitis
staph aureus
What type of infectious agent causes non-blanching cellulitis
strep
What infectious agent is most commonly seen after cat bites?
Pasteurella multocida
What are the IDSA guidelines for clinical classification of a diabetic foot infection?
Mild - signs of inflammation, such as pain and induration, cellulitis 2 cm of less around ulcer

Moderate - cellulitis > 2 cm around ulcers, lymphangitis, spread beneath fascia, abscess, gangrene

Severe - local infection with systemic toxicity (fever, hypotension, leukocystosis or azotemia)
For mild Diabetic foot infections what is the duration of antibiotic therapy?
10-14 days
For moderate and severe diabetic foot infections how long should you keep the patient on antibiotic therapy?
2-4 weeks
What is the dose for Zosyn?
3.375 g q6h
What is the dose for Augmentin and what is it's spectrum of activity?
875 mg BID
strep, gram negative aerobes, anaerobes, staph
(not pseudomonas)
what is the dose of Timentin?
IV 3.1 gram q6h
What would be the drug of choice for staphylococcus methicillin sensitive species?
Cephalexin 250 mg PO QID
What are some PO alternatives to cephalexin to treat staphylococcus methicillin sensitive species?
Clindamycin 300 mg PO QID
Dicloxacillin 250 mg PO QID
Azithromycin 500 mg as a single dose on day 1, followed by 250 mg daily on days 2-5
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