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Medical Microbiology Test 4
A substance derived from a microbe that will inhibit or destroy another microbe.
65% of antibiotics are derived from:
Sulfur drugs treat...
Where do most antibiotic-producing microbes come from?
The ability of a drug to attack a pathogen and not the tissues.
A therapeutic dose should be....
...a low but effective dose.
The toxic dose of an antibiotic should be...
...high enough to avoid damaging the patient.
Chemotherapeutic dose equals...
The toxic dose divided by the therapeutic dose.
A chemotherpeutic dose should be...
...high with few side effects.
Toxicity is measured (blank).
Side effects are the measurement for (blank).
Kills a pathogen
Prevents multiplication or growth in a pathogen.
Inhibition of cell wall synthesis has...
...a high chemotherapeutic index.
Influencing factors on effectiveness of an antimicrobial drug.
-Pathogen must be suseptible to drug.
-Drug must be able to reach site of infection
-Drug must be able to reach infection at the correct concentration.
Effectiveness of a drug depends on...
-Rate of Elimination
A synthetic antibacterial drug that targets metabolic pathways and is composed of sulfur.
An antibiotic or semi-synthetic antimicrobial that acts on mostly Gram + microbes.
An antibiotic that inhibits cell wall synthesis and can be used in place of penicillin.
A very toxic drug that inhibits RBC production. Only used in extreme situations.
A 4-ringed structured drug.
A macrolide antibiotic produced by Streptomycin.
A drug that inhibits cell wall synthesis, is used against resistant strains as a "last resort".
Three antimicrobials in neosporin.
Vancomycin Resistant Staphylococcus Aureus
Multi-drug Resistant Staphylococcus Aureus
What drug is gonorrhea now resistant to?
(blank) is damaged in penicillin to inactivate it.
The beta-lactam nucleus ring structure
Acquisition of a new R plasmid
The most common way for a microbe to develop resistance.
An anti-fungal developed from streptomycin to fight yeast infections
An anti-fungal developed from penicillin to fight Athlete's foot.
A powerful anti-fungal developed from streptomycin that fights systemic fungal infections
The hardest microbe pathogen to target.
A drug that blocks the attachment of a virus, commonly used against the flu.
A drug that inhibits viral nucleic acid synthesis. Used against the herpes virus.
Used against HIV. Blocks reverse transcriptase.
The species classified by letter (A-O) depending on a carbohydrate present in the cell wall.
Two complications of Strep Throat
Bacteria infection and multiplication in the blood.
The causative agent of Diptheria
The causative agent of Pertussis (Whooping Cough).
A causative agent of Meningococcal Meningitis
Another causative agent of Meningitis
Haemophilus influenzae B
A stage of TB when the bacteria enters the blood after latent period.
An old name for Tuberculosis
Direct Observation and Treatment System
A test for exposure to TB.
80% of bacterial pneumonias are caused by this agent.
The causative agent of Primary Atypical Pneumonia (Walking Pneumonia)
Mycoplasma penumoniae appear as a (blank)-shaped colony on agar.
Diseases in which bacterial toxins are injested and cause disease.
Diseases in which actual bacteria are injested and cause disease.
Infection incubation depends on these three aspects.
-Virulence of pathogen
-Type of bacteria
The type of toxin that acts on the GI tract.
Food poisoning is normally caused by this agent.
Staphylococcus Food Poisoning is an (blank).
The causative agent of Botulism.
The type of toxin produced by C. botulinum
The botulisum toxin attacks what neurotransmitter?
Acetylcholine, leading to no muscle contraction.
70% of botulisim intoxications are in the (blank) population.