Satan - Head of the rebellious angels who have just fallen from Heaven. As the poem's antagonist, Satan is the originator of
Adam - The first human, the father of our race, and, along with his wife Eve,
Eve - The first woman and the mother of mankind.
God the Father -
Belial - One of the principal devils in Hell. Belial argues against further war with Heaven, but he does so because he is an embodiment of sloth and inactivity,.
Mammon - A devil known in the Bible as the epitome of wealth. Mammon always walks hunched over, as if he is searching the ground for valuables.
Mulciber - The devil who builds Pandemonium, Satan's palace in Hell.
Moloch - A rash, irrational, and murderous devil. Moloch argues in Pandemonium that the devils should engage in another full war against God and his servant angels.
Sin - Satan's daughter, who sprang full-formed from Satan's head when he was still in Heaven. Sin has the shape of a woman above the waist, that of a serpent below, and her middle is ringed about with Hell Hounds, who periodically burrow into her womb and gnaw her entrails. She guards the gates of Hell.
Death - Satan's son by his daughter, Sin. Death in turn rapes his mother, begetting the mass of beasts that torment her lower half.
Gabriel - One of the archangels of Heaven, who acts as a guard at the Garden of Eden.
Raphael - One of the archangels in Heaven, who acts as one of God's messengers. Raphael informs Adam of Satan's plot to seduce them into sin, and also narrates the story of the fallen angels, as well as the fall of Satan.
Uriel - An angel who guards the planet earth. Uriel is the angel whom Satan tricks when he is disguised as a cherub.
Abdiel - An angel who at first considers joining Satan in rebellion but argues against Satan and the rebel angels and returns to God. His character demonstrates the power of repentance.
Michael - The chief of the archangels, Michael leads the angelic forces against Satan and his followers in the battle in Heaven,