Prevention of nausea & vomiting induced by chemotherapy, radiation delayed gastric emptying, and GERD
Blocks dopamine receptors in chemoreceptor trigger zone of the CNS.
Stimulates motility of the upper GI tract and accelerates gastric emptying.
drowsiness, extrapyramidal reactions, restlessness, NEUROLEPTIC MALIGNANT SYNDROME,
Assess for nausea, vomiting, abdominal distention, and bowel sounds before and after administration.
Assess for extrapyramidal side effects
Use with tube feeding to decrease residual and risk of aspiration
PO: take 30-60 minutes before meals or procedures
IV: inject slowly over 1-2 min, Infuse over 15 min
Use caution with potentially hazardous activities
Avoid alcohol, CNS depressants
May cause tardive dyskinesia or neuroleptic malignant syndrome when uses for longer than 3 months
May cause depression
Lab Test Considerations:
May alter hepatic function test results.
May cause ↑ serum prolactin and aldosterone concentrations.
Use: Local anesthesia
Class: Local anesthetic (amide)
AEs: Cardiovascular toxicity, various CNS symptoms (excitation or depression, dizziness, seizures), allergic reactions.
Local or regional anesthesia or analgesia for surgical, obstetric, or diagnostic procedures.
Local anesthetics inhibit initiation and conduction of sensory nerve impulses by altering the influx of sodium and efflux of potassium in neurons, slowing or stopping pain transmission.
Decreased pain or induction of anesthesia; low doses have minimal effect on sensory or motor function; higher doses may produce complete motor blockade.
SEIZURES, CARDIOVASCULAR COLLAPSE
Systemic Toxicity: Assess for systemic toxicity (circumoral tingling and numbness, ringing in ears, metallic taste, dizziness, blurred vision, tremors, slow speech, irritability, twitching, seizures, cardiac dysrhythmias). Report to physician or other health care professional.
Monitor BP, HR, and respiratory rate continuously while patient is receiving this medication.
Monitor for return of sensation after procedure.
Allergy, anaphylaxis, sedation, motion sickness, antitussive
Antagonizes effects of histamine, CNS depression
T: Allergy, cold & cough remedy, antihistamine, antitussive
May cause drowsiness, anorexia, dry mouth, nausea, chest tightness, thick secretions, hypotension, blurred vision, headache
Anticholinergic effects (dry mouth, blurred vision, constipation, sedation)
Assess purpose of medication prior to giving it
Assess allergies, sleep patterns, cough & lung sounds
Patients should avoid other over-the-counter cough & cold remedies
Moderate to severe chronic pain in opioid-tolerant patients requiring use of daily, around-the-clock long-term opioid treatment and for which alternative treatment options are inadequate (extended-release).
Transdermal fentanyl is not recommended for the control of postoperative, mild, or intermittent pain, nor should it be used for short-term pain relief.
Binds to opiate receptors in the CNS, altering the response to and perception of pain.
confusion, sedation, weakness, APNEA, RESPIRATORY DEPRESSION, anorexia, constipation, dry mouth, nausea, vomiting, sweating
GRAPEFRUIT JUICE - moderate inhibitor of the CYP3A4 enzyme system; concurrent use may ↑ blood levels and the risk of respiratory and CNS depression. Careful monitoring and dose adjustment is recommended.
Transdermal patch lasts 72 hr in most patients. Some patients require a new patch every 48 hr