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single ancestral cell
all the cells within primary and secondary tumors are generated by multiple divisions of this
Tumorogenesis requires successive mutations in genes that control:
the inability to repair normal DNA damage is a fundamental characteristic of cancer cells
hereditary sensitivity to UV light results from defects in nucleotide excision repair
apoptotic cells fragment their DNA and split into small _____ that are taken up by phagocytic cells
implantation of embryo in uterus
immune cells targeting infection
invasion of tissues that is normal for human cells
decreased levels of E-cadherin
increased levels of proteolytic enzymes
Metastatic cancer cells may show
tumors suppressor genes
normally halt the cell cycle in response to extracellular signals or DNA damage
mutations causing tumor suppressor genes to ___ function result in cells that divide when they should be quiescent
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