Clin Path Exam 1
Terms in this set (48)
occupational safety and health administration
OSHA What government entity oversees safety and mandates specific laboratory standards? And what is it's abbreviation?
how closely results agree with the true quantitative value of a constituent
Magnitude of random errors and reproducibility of measurements
Ability of a method to be accurate and precise
increased frequency of urine
absence of urine
SG approaches that of glomerular filtrate (no concentration or dilution)
SG less than glomerular filtrate and truly diluted
blood in the urine intact RBC's
- Can see in urine sediment Bleeding in urinary tract UTI's ,neoplasia
Intravascular hemolysis (IMHA, transfusions, lepto)
After centrifuging, the supernatant (upper liquid part)will remain red
Could happen if RBC's rupture in very dilute urine
presence of myoglobin in urine Severe muscle damage
Dark brown in color, sometimes hard to tell apart from hemoglobinuria
destruction of red blood cells
Excessive amount of fat in the blood
Generates reliable lab results
What is your role as veterinary technician in a clin path lab and obtaining valid results?
Material Safety Data Sheet
What is an MSDS or SDS?
( T/F) When chemicals are moved from a primary container to another container, a secondary label must be applied.
What are two types of blood-borne pathogens?
Personal Protective Equipment
What does PPE do? And what are examples? (keeps us safe, goggles, lab coat, gloves)
Biosafety levels- which ones will cause you harm?
Must have infectious substance label
Sealed in leakproof containers
Surrounded by a layer of watertight material
Absorbent material between each layer
12. What are 4 most common equipment even in a minimal lab?
Specific gravity, protein concentrations
What is a refractometer and how is it calibrated? (Can calibrate with distilled water)
What are 2 major lab tests run in house?
centerfuge, loops, fecalizers
Fecals- How run and what are you looking for?
Urinalysis- How to obtain sample?
Strip tests are?
Accuracy, precision, and reliability
what are hallmarks of quality assurance?
What is the basic functioning unit of the kidney?
how urine is formed
blood enters renal corpuscle-
-plasma and wastes are filtered through the glomerulus in the next portion of the proximal convoluted tubule
large proteins and cells do not enter unless damaged
filtered fluid passes through the rest of the nephron
water and glucose are resorbed back into body
volume, color, odor, transparency, specific gravity
what are the 5 physical properties studied in a urinalysis
varies with SG
color- what is normal? varies with?
clarity/transparency- most urine is....... what animal might not be and why? (horse- cloudy because of calcium carbonate crystals and mucus
rabbit- calcium carbonate crystals cause milky urine
porphyrin pigment in diet causes red urine)
odor- is this highly diagnostic? Y or N
weight or density of a quantity of liquid compared with that of an equal amount of distilled water
measure degree of acidity or alkalinity of urine
concentration of hydrogen ions
kidneys do not allow any through its filtration
done mostly with strips
other tests- microalbuminuria, sulfosalicylic acid turbidity, and urine protein ratio
filtered through the glomerulus and then resorbed by the kidney tubules
glucose has to reach threshold to spill over into urine
formed during incomplete catabolism of fatty acids
generally abnormal if seen
seen in urine as a response to high levels of bilirubin in the blood stream
hematuria- intact RBC's
-can see in urine sediment
-bleeding in urinary tract
hemoglobinuria- free hemoglobin
-after centrifuging, the supernatant will remain red
-could happen if RBC's rupture In very diluted urine
presumptive evidence of leukocytes
can have false positive
need to check sediment for WBC
little to none
urine sediment- what is normal? is some sediment normal in some animals?
how do you test for sediment?
urolithiasis- definition- where found