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19 terms

Final- GI 2

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Shigella dysenteriae
Dysentery
Low infectious dose (10 bacteria)
toxico-infection; Shiga neurotoxin (AB)
lactose -
symptoms of Shigella dysenteriae
1-4 day incubation period--- bloody and watery diarrhea, mucus (> 20 stools/day) for 2-7 d
Shigella dysenteriae treatment
Rehydration, TMP-SMX
5 Fs
Shigella dysenteriae transmitted by:
#1 cause of mortality in children world wide; fecal-oral
Campylobacter jejuni
Diarrhea
Heat labile entertoxin
Symptoms of Campylobacter jejuni
Frequent watery stools, fever, vomiting, headache and abdominal pain -2weeks
treatment of Campylobacter jejuni
oral rehydration and electrolyte replacement, erythromycin
Campylobacter jejuni transmitted by :
food prep, sanitary water
Guillain-Barré
Vibrio cholerae
Cholera
toxogenic = AB toxin coded on a plasmid that upregulates cAMP --> H2O & electrolyte loss
symptoms of Vibrio cholerae
clear watery diarrhea, rice-water stools
Vibrio cholerae is transmitted by:
fecal-oral; sanitation
**V. parahaemolyticus causes epidemic shellfish enterocolitis
what are the symptoms of Escherichia coli?
Enterotoxigenic E. coli (ETEC) or dysentery (shiga-like, enteroinvasive (EIEC))
diagnosis of Escherichia coli:
lactose +; typing
---enterotoxin (AB exotoxin)
Escherichia coli is transmitted by :
normal flora; fecal-oral. EHEC (O157:H7) causes bloody diarrhea--- HUS
infective dose < 10 organisms
Helicobacter pylori & symptoms
likes acid environment; tropism for gastric mucosa
dyspepsia, gastritis
painful stomach and duodenal ulcers
diagnosis of Helicobacter pylori
breath test for urease; endoscopy
Clostridium difficile
Pseudomembranous Colitis
>>>also called antibiotic associated colitis because it follows broad spectrum antibiotic usage
Normal flora; nosocomial
Symptoms of Clostridium difficile
toxin induced diarrhea
Diagnosis of Clostridium difficile
Tox test