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Inbred Mouse Strains

Terms in this set (7)

Sensitivity to radiation
Used in hybridoma technology
Many Myeloma cell lines were generated in these mice

High incidence of hepatomas after irradiation
High Complement activity

Very close relationship to C5BL/6 but differences in at least two loci

Frequent partner in preparation of cogenic mice

high incidence of autoimmune hemolytic anemia and lupus-like nephritis

Autoimmune disease similar to systemic lupus eythromatosus (SLE)

SLE-type autoimmune disease in F1 progeny from crosses with NZB

High incidence of leukemia

high level of agression and severe fighting to the point of death , esp in males

Tendency to develop certain autoimmune diseases, most susceptible to EAE.

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