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Circadian Rhythms

Terms in this set (28)

Cyclic event within a 24 hour period
A circadian rhythm is a _____
Internally
Circadian rhythms of body functions are generated _____
Constant conditions
Circadian rhythms persist under _____ within a 24 hour period
1. Sleep/wake cycle
2. Body temperature
3. Pattern of hormone secretion
4. Blood pressure
5. Digestive secretion
6. Alertness
7. Reaction times
Circadian rhythms are physiological and behavioral and include (7)
Suprachiasmatic nucleus
_____ is the master circadian oscillator
Input from the retina
The core of the suprachiasmatic nucleus receives _____
Output to other brain areas
The shell of the suprachiasmatic nucleus sends _____
Core of SCN
Green portion
Shell of SCN
Red portion
Tau
The period, or time between successive cycles is also known as ____
24
Period between successive cycles may not be exactly ____ hours
Locomotor circadian rhythms
Lesions of SCN result in loss of ____
In vitro
SCN explants (extracted) maintain rhythmic activity _____
22 hours
Tau mutation in golden hamster (heterozygous) was ____
20 hours
Tau mutation in golden hamster (homozygous) was ____
Donor SCN
Period of locomotor rhythm is determined by ____
Multiple CNS sites
SCN projects to ____ that control circadian rhythms
External time cues (light-dark cycles)
Entrainment is synchronization to _____
SCN
Not all information from the retina go to the LGN, some go to the ____
Melanopsin
Intrinsically Photosensitive Retinal Ganglion Cells (ipRGCs) have the photopigment ____
Retinohypothalamic pathway (RHT)
____ is the pathway from retina to SCN
Blue
ipRGC's are most sensitive to ____ light
4
Molecular clock is made up of ____ genes
1. Primary feedback loop

2. Core clock genes
Molecular clock is made up of (2)
24 hours
The transcriptional-translational feedback loop lasts about ____
Morning chronotype (morning lark)
The circadian phenotype where you go to bed early and get up early is known as ____
Evening chronotype )night owl)
The circadian phenotype where you go to bed late and get up later is known as ____
Social jet lag
_____ is a mismatch between your internal clock and the social clock
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